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THC Suppositories: The Benefits for Abdominal Cramps & Pain Did you know that pollen from a Cannabis plant was found on the mummy of Ramesses II, who died in 1213 BC? In fact, it was noted in an The back door is making a comeback – medically speaking. Cannabis oil suppositories have grown in popularity, but how and to what extent they actually work remains somewhat of a mystery. Created for Anal and Vaginal Sex. These suppositories relax your muscles allowing deep penetration and promote blood flow —HELLO ORGASM.

THC Suppositories: The Benefits for Abdominal Cramps & Pain

Did you know that pollen from a Cannabis plant was found on the mummy of Ramesses II, who died in 1213 BC? In fact, it was noted in an Egyptian medical papyrus of herbal knowledge from 1550 BC (Ebers Papyrus) that medical cannabis can be effective in treating inflammation. 1 Not only that, but there is also evidence to suggest that the ancient Egyptians used cannabis for a wide range of medical applications including enema’s and to help cool the uterus. 2

So, although cannabis suppositories might seem like a new thing for some, their use for medicinal purposes actually goes back thousands of years.

What Makes THC Suppositories Different?

So, what is it about rectal and vaginal THC Suppositories that makes them different from other methods of ingesting cannabis? Before we answer that, let’s define exactly what cannabis suppositories are.

THC and CBD suppositories are round, cone-, or bullet-, shaped doses of medicine that are inserted into the rectum or vagina. Once the suppository is inserted, it melts and releases the healing power of cannabinoids into our bodies. Cannabis suppositories can contain THC or CBD, or a combination of both. They will often use ingredients like coconut oil, avocado oil, or cocoa butter as a base since cannabinoids are fat soluble.

Suppositories are considered to be an effective way for those experiencing severe nausea or vomiting to medicate.

How Suppositories Work

First of all, suppositories go to work quicker than other forms of cannabis consumption. Although more research needs to be done, what we do know is that suppositories allow the THC and CBD to be absorbed quickly into our bodies through rectal or vaginal mucosa.

Since cannabinoids like THC and CBD are fat-soluble, they’re able to be absorbed into our body tissue and spread locally. This can be thought of similar to a topical cream that you apply to the area you are seeking relief. But instead of applying it to your skin, suppositories release the healing power of cannabis internally in a more localized and targeted manner.

This is different from other methods of ingesting cannabis where cannabinoids enter our bloodstream and are circulated throughout our bodies.

Benefits of THC & CBD Suppositories

Since the pelvic region of our bodies are filled with muscles, nerves, and cannabinoid receptors, this can make suppositories effective in treating issues that are close in proximity to our mid-sections and lower bodies..

This is especially true when suppositories contain both THC and CBD. That’s because this allows your body to benefit from what is known as the entourage effect–which basically says that by ingesting THC and CBD together, patients can enjoy a more complete cannabis experience.

Some of the benefits that have been attributed to suppositories containing both THC & CBD include:

  • Relief of lower back, hip, bowel, and menopausal pain and discomfort
  • Reducing inflammation related to hemorrhoids and Crohn’s Disease
  • Alleviating muscle and menstrual pain

Now that you have a better understanding of some of the benefits of medicating with cannabis suppositories, let’s examine the similarities and differences between Rectal & Vaginal suppositories.

Rectal & Vaginal Suppositories

Many THC and CBD suppositories can be used through either the rectum or the vagina. The best way to medicate will come down to your personal preference, body type, product type, and the benefit you are seeking.

THC Rectal Suppositories

According to recent research, the bioavailability of cannabis through rectal absorption is about twice that of oral absorption. 3 That means that our bodies can absorb twice the amount of health-enhancing cannabinoids like THC and CBD when we ingest cannabis rectally vs. orally.

This can make rectal suppositories a great way to maximize the health benefits of medical cannabis in a cost-efficient manner.

Rectal suppositories have been thought to help treat:

  • Prostate problems
  • Hemorrhoid inflammation
  • Digestive issues
  • Lower back pain

THC Vaginal Suppositories:

Although research on the bioavailability of THC and CBD within the vagina is still in its early stages, it is believed that the vagina and female reproductive tract are filled with cannabinoid receptors. This can make vaginal suppositories a great way to maximize the therapeutic benefits of THC and CBD.

Vaginal suppositories have been thought to help alleviate discomfort from:

  • Abdominal pain
  • Menstrual cramps
  • Menopause
  • Pelvic tension and discomfort
  • Pain during intercourse

Either Way, Suppositories Can Provide Relief Where You Need It Most

Since cannabinoids are fat soluble, rectal and vaginal suppositories allow our bodies to quickly absorb THC and CBD and release their healing powers to the area where we need it most.

By doing so, most patients will be able to enjoy the therapeutic benefits of THC without the psychoactive effects commonly associated with it. Which brings us to a frequently asked question…

Will THC Suppositories Make You Feel High?

Often, one of the questions that comes up with suppositories is “will THC suppositories make me feel high?” For the most part, the answer is no.

Although research on cannabis suppositories is limited, the majority of those who medicate with cannabis suppositories do not experience psychoactive effects. So, for most, THC suppositories can be an effective way to enjoy the healing benefits of cannabis without experiencing the psychoactive effects of THC.

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However, it is important to note that everyone’s experience with cannabis will be different. Some people have reported feeling full-body highs after medicating with THC suppositories. So, if you are new to suppositories it is best to start slowly as far as dosing goes.

THC Suppository Frequency and Dosage

In general, when it comes to suppositories, most people will find that they can handle higher doses of THC without feeling its psychoactive effects. This can make suppositories suitable for those who need stronger dosages of medication without feeling high.

As with any other method of ingesting THC or CBD it is best to start slowly and build from there. If you are new to THC, it would be good to start with a 10 mg dose.

As far as frequency goes, it will vary. If you are using them to help relieve lower back pain, you would only use them when the pain arises. On the other hand, if you are taking them to help reduce the discomfort of menstrual cramps, then you might use suppositories for a few days when your cramps are the worst.

How to Use a Suppository

First, suppositories are much easier to insert and less messy if they are firm to the touch.

So, you’ll want to start by placing your suppositories in the refrigerator ahead of time. Although you’ll only need a few minutes of refrigeration to achieve the right amount of firmness, most manufacturers recommend keeping them refrigerated.

Next, you will want to wash your hands.

Then, you’ll want to take your underwear off and get into a position that will make it easy to insert the suppository. Some might place a leg up on the bathtub, while others might lay on their backs and pull their knees toward their chest.

Once you are in position, you can go ahead and place the suppository on the tip of your finger and press the suppository into the rectum or vagina. If you like, you could use a little bit of lubricant..

It will generally take 15 – 20 minutes for the suppository to melt and be absorbed into your system.

It might be a good idea to insert your suppository ahead of a time that you will be lying down for a bit, like bedtime. This way you can avoid any potential leakage.

Potential Side Effects

There have been very few reported adverse effects from medicating with THC and CBD suppositories. For anyone dealing with allergies it is very important to examine the list of ingredients in that suppository to make sure it does not contain anything that could cause an allergic reaction.

As with any type of medicine, it is important to consult with your physician before introducing a new form of medication. Your doctor can help to determine if there are any potential risks or side effects depending on your current condition and any medications you might be taking.

Final Considerations When Medicating with Suppositories

One thing to keep in mind when considering medicating with suppositories is that THC suppositories are not legal in all 50 states. However, CBD suppositories that do not contain THC are.

Want to learn more about our available products? Shop at Bloom to check our available inventory!

Do Cannabis Suppositories Work?

The back door is making a comeback – medically speaking.

Cannabis suppositories have grown in popularity, but how and to what extent they actually work remains a mystery. With contradictory claims from proponents and skeptics regarding the rectal bioavailability of THC , intoxication (or lack thereof), and alleviation of symptoms of difficult-to-treat diseases, it’s time to get a grip on what we really know about this method of administering cannabis.

Clinical research on cannabis suppositories is still limited. Much of the available data pertains to experiments conducted on animals, not on people who actually use suppositories. Despite the distinct lack of clinical studies, anecdotal accounts from patients are often very positive. The overwhelming majority of patient reports have one thing in common: a lack of intoxication that’s typically caused by smoking or ingesting THC -rich cannabis.

The absence of a “head high” would seem to indicate that a suppository does not distribute a systemic dose of cannabis – which corroborates initial research findings about limited bioavailability. This suggests that a suppository acts more like a topical with a local effect, rather than a transdermal patch which disseminates medicine systemically through the bloodstream.

Why suppositories?

Rectal and vaginal suppositories have both been used to deliver medicine to patients for decades. The pelvic region houses a matrix of nerves that travel to the legs and up the spine, and the colon contains cannabinoid receptors ( CB 1 and CB 2), which mediate many of THC ’s effects.

Generally, cannabis suppositories are made by combining cannabis-infused oils in a carrier oil that hardens at low temperatures. Rectal administration of cannabis oil may activate the cannabinoid receptors located there, which could be beneficial for local conditions like hemorrhoids or acute inflammation [6]. The rectum also contains a number of key veins that deliver blood to the entire body, but it doesn’t appear that suppositories facilitate cannabinoid absorption into the bloodstream.

Even if they are only effective locally rather than systemically, suppositories may offer a viable alternative to patients suffering from conditions that render them unable to ingest their prescriptions orally [1]. Issues with palatability, severe nausea or vomiting, compromised esophageal or gastrointestinal tracts, and a range of other symptoms can make oral administration an impossibility for many patients.

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Clinical research

A number of studies have called into question the rectal bioavailability of THC . In a 1985 study, researchers found no circulating levels of Δ9 THC in blood plasma after rectal administration of THC . According to University of Mississippi pharmacologist and researcher Dr. Mahmoud ElSohly, this means that in commercially available formulations THC is not absorbed into the bloodstream via the rectum at all.

ElSohly claims that any cerebral intoxication experienced using cannabis suppositories is a result of the placebo effect rather than the activation of the CB1 cannabinoid receptors in the brain – which is what makes us feel high from THC .

Interestingly, a later study showed that a chemically modified version of THC , called THC -hemisuccinate (or THC – HS for short), is bioavailable in the rectum. Succinate, an intermediate compound in the breakdown of sugar, is slightly water soluble, which allows it to be absorbed through the rectal mucosa. It was first synthesized at ElSohly Laboratories, Inc. Unlike regular THC , THC from the hemisuccinate ester was found to easily permeate and absorb into rectal mucus membranes [7], then enter into circulation as Δ9 THC . As a result, most of the THC avoided first-pass metabolism and did not transform into its more psychotropically potent metabolite, 11-hydroxy- THC , in the liver [5].

“ElSohly claims that any cerebral intoxication experienced using cannabis suppositories is a result of the placebo effect.”

The results from a follow-up 1996 pilot study support the idea that THC – HS administered rectally could result in improvement in symptoms of spasticity, rigidity, and pain, while producing no measurable differences in cardiovascular function, concentration, and mood of the participants – in other words, without signs of measurable intoxication.

Most recently, in 2018, ElSohly and his team found that the concentration of Δ9 THC in blood plasma after rectal administration of a THC – HS suppository was about 70-80% bioavailable, almost 2.5 times higher than an orally ingested THC capsule. While there were no reports of intoxication for the test subjects, the paper states that first-pass metabolism was “greatly reduced,” although not eliminated entirely. This means that some slight psychotropic effects from the 11-hydroxy- THC could still be possible with THC – HS formulation, but more studies are necessary to confirm this.

ElSohly’s research could have significant implications for cancer patients and others suffering from conditions that may require very high doses of cannabinoids but who are unable to smoke or ingest their medicine. THC – HS , however, is a patented molecule and can only be prepared with a license from the University of Mississippi.

Pain relief and pleasure

Cancer patients* and people with compromised upper alimentary tracts will likely have to wait some time before THC – HS formulations become commercially available. Meanwhile, THC and CBD -rich suppositories are currently being sold in state-licensed cannabis dispensaries.

Ben Odell, content director at Foria Wellness, a cannabis producer based in California and Colorado, says that the best way to conceptualize the effects of suppositories is by imagining them as powerful topicals – except they are applied internally. Just as externally applied topicals interact with cannabinoid receptors in the skin, rectal suppositories are aimed at nerve endings and cannabinoid receptors in colonic tissue.

“Everyone is debating and discussing rectal absorption of THC , and whether [cannabis oil extracts] and other formulations are absorbed into the bloodstream or not. But we’re not interested in getting people high,” says Odell. Instead their focus is on creating products that alleviate pain and discomfort in the lower body, as well as products that enhance intimate pleasure.

“Odell says that customers and Foria staff have been experimenting with cannabis suppositories for relief of other lower-body issues, like cramping, inflammation, and pelvic discomfort – with good results.”

Foria initially launched their mixed THC : CBD ratio rectal suppository as a sexual aid. “We were hearing from our friends in the queer community that a lot of people use nasty chemicals to relax the anal sphincter before sex — things like ‘poppers,” Odell told Project CBD . The idea behind the new product line is that THC and CBD could help mitigate painful localized inflammation and relax smooth muscle tissue – like the involuntary muscle tissue of the internal sphincter [9]. Odell says that customers and Foria staff have been experimenting with cannabis suppositories for relief of other lower-body issues, like cramping, inflammation, and pelvic discomfort – with good results.

Foria also produces a high- CBD suppository and a high- THC formula for vaginal application. Odell reports that feedback regarding THC -rich suppositories has been far more positive for pain relief than the CBD line. This summer Foria will be partnering with Harvard neuroscientist Dr. Staci Gruber to conduct a study that will track women’s responses to CBD suppositories.

Who can benefit?

Whether or not cannabinoids are absorbed into the bloodstream from the rectum, many suppository enthusiasts report powerful, localized, non-psychotropic effects for a range of middle and lower body afflictions.

Anal Suppositories

Men and women have reported using rectal suppositories to treat anal fissures, hemorrhoid inflammation, digestive issues, Crohn’s and IBS , sciatica, restless leg syndrome, lower back pain, prostate issues, and post-operative pain. Rectal suppositories are also being used for lubrication to mitigate pain during anal intercourse.

Vaginal Suppositories

Vaginal suppositories have been used to ease menstrual cramps, abdominal pain, endometriosis, pelvic discomfort, post-coital pain or inflammation, vaginal dryness and pain with intercourse, as well as for relaxation and sexual enhancement.

Of course, dosing via the vagina or rectum is not as simple as taking a puff or swallowing a pill (lest we forget about gravity). Cannabinoids are tricky molecules and there’s still much to learn scientifically and pragmatically about the efficacy of various delivery systems, including cannabis suppositories.

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Thus far, clinical studies have shown no rectal bioavailability of unadulterated THC [2,7]. And while it’s plausible to speculate that cannabinoids could have an effect via local pathways in the colon and elsewhere, those pathways haven’t been studied yet. Although many anecdotal reports are positive, there are some significant discrepancies in observed efficacy [9]. Far more research is needed to better understand exactly how this method works (or doesn’t).

But there’s no need for patients to wait until all the results are in. If you’re curious, suppositories could be worth a try. You probably won’t get a “head high,” according to the legendary Tommy Chong, who uses cannabis suppositories under a doctor’s supervision. Though you might feel a little “butt high,” Chong says with a smile, which is not necessarily a bad thing.

How To Make Your Own Suppositories

If you want to try suppositories at home, you have a few options: you could find them at your local dispensary, order online, or make them yourself with a few simple ingredients.

What You Need

  • Full-extract cannabis oil of your choice
  • A base (organic cacao butter or coconut oil are recommended)
  • Suppository molds (these can be metal, silicone, or plastic)

Instructions

  • Gently heat the base in a pan.
  • Add in the cannabis oil of your choice and mix well.
  • Pour the mixture into the suppository mold and pop it into the freezer.

Tips and Tricks for Use

  • While the onset of effects is highly variable, users typically report feeling effects within 30-60 minutes for vaginal application and 15-30 minutes with rectal administration.
  • The base will melt quickly during contact with warm skin, so keep the suppositories in the freezer until you’re ready to medicate.
  • You can prevent leakage by lying in a horizontal position during insertion and for at least 15-30 minutes after.
  • Try using them at night your first few times. It’s always better to be familiar with potential effects before daytime use.
  • Record your experiences in a journal to identify your patterns and best practices.

(Recipe courtesy of Paula-Noel Macfie)

* Suppositories are not reccomended for use by cancer patients undergoing chemotherapy. According to Dr. Bonni Goldstien, “chemo causes thinning and sloughing of cells of the lining of mucus membranes (which is the tissue of the mouth and rectum) and also decreases the ability of the immune system to fight infection” and inserting a suppository could introduce infection-causing bacteria.

Jelena Grove is a cannabis writer and budtender based in Portland, OR . This is her first article for Project CBD .

Copyright, Project CBD . May not be reprinted without permission.

Mello Bottoms ~ CBD Suppositories

Before you say, “you want me to put what in where ?” just hear us out. We know suppositories probably weren’t the first thing you thought of when you started looking up ways to get your CBD dose. We’re willing to bet they weren’t your second, or third, or even fourth thought either. People are afraid to talk about them — but not us.

Etch out some time in your calendar to unwind, and then let the Mello Bottoms take you there! These are great for total relaxation. For sexy time – these increase sensitivity and sensation while aiding with dryness, and lubrication. And can be also used for lower body discomfort from your period or IBS.

These make it easy for you to administer your CBD dose. Since CBD has greater bioavailability and absorption when administered in this manner, you’ll start to feel the effects of your 75mg dose in just 10 minutes. Bottoms up, baby.

  1. Wash hands with soap and warm water.
  2. Remove suppository from the fridge and remove wrapper.
  3. Lubrication is key! Apply a water-soluble lubricant to the application area as well as to the tip of the suppository.
  4. Insert in your vagina or your bottom. We personally prefer our booty hole.
  5. Wash your hands thoroughly.
  6. Rest for 5-20 minutes so the suppository can settle in and won’t slip out.
  7. Enjoy the relaxation!

For anal insertion, lie on your side and straighten your lower leg while bending your upper leg toward your stomach. Lift upper buttock, and insert the suppository until it passes the muscular sphincter of the rectum — this is about 1 inch in most adults!

For vaginal insertion, insert the suppository (pointed end first) with your finger as far back as it can go without causing any discomfort.

Organic Coconut Oil

Full Spectrum Cannabis Hemp Extract with CBD

Organic Hemp Oil

Organic Cocoa Butter

  • These are great for total relaxation.
  • For sexy time – these increase sensitivity and sensation while aiding with dryness, and lubrication.
  • Will provide relief to lower body discomfort from your period or IBS.
  • Helps relieve pain, reduce anxiety, lift mood and remedy insomnia
  • Promotes insulin function

75MG of CBD per Suppository

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. more

Orders are processed and shipped Monday through Friday from 9am to 5pm EST (excluding holidays) with 5-7 business-day delivery on all US orders with our flat rate shipping.

If placed after 5pm on Friday, the order will be fulfilled the following Monday.

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