There is a lot of controversy surrounding cannabidiol (CBD oil) and other cannabis-derived products, so Aeroflow Sleep went to the experts. What You Need To Know About CBD And Sleep There’s nothing worse than not being able to sleep. You toss and turn, maybe check your phone a few times, and worry as minutes ticks away, leaving with Does sleep apnea bother you at night? Learn how you can use CBD oil to reduce the symptoms and improve the quality of your sleep.
Can CBD Oil Really Help Sleep Apnea Patients Like You (Even on CPAP Machines?)
There is a lot of controversy surrounding cannabidiol (CBD oil) and other cannabis-derived products, so Aeroflow Sleep went to the experts. THC Design, a leading cannabis cultivator in California, partnered with us to educate sleep apnea patients like you on how CBD oil can really help (even on CPAP machines,) and our Sleep Science Advisor, Dr. Carleara Weiss backed them up.
Table of Contents
What is Sleep Apnea?
Sleep apnea is a common condition that affects millions of people worldwide. The condition is characterized by pauses in breathing during sleep. It can generally be classified into three types: obstructive sleep apnea, central sleep apnea, and complex sleep apnea.
Obstructive sleep apnea is the most common form of sleep apnea. The condition is caused by a blockage of the upper airway. This causes a decrease in the flow of oxygen to the brain, which leads to a decrease in blood oxygen levels.
Meanwhile, central sleep apnea is caused by a decrease in the activity of the brain’s respiratory center. The respiratory center controls the flow of air into the lungs and is also responsible for regulating one’s breathing. When it is not functioning properly, the respiratory center fails to send signals to the muscles to open and close the airway. This results in pauses in breathing.
Complex sleep apnea, also known as mixed sleep apnea, is caused by both obstructive and central sleep apnea.
What You Need to Know about CBD and Sleep
Cannabidiol (CBD) has long been used as a natural remedy for a variety of conditions from anxiety and chronic pain to seizures and sleep disorders. In fact, a recent study found out that about 66.7% of people who used CBD have experienced some sort of relief from their sleep problems.
What is CBD?
CBD is one of the most potent compounds found in various cannabis strains. It is a non-psychoactive cannabinoid that is widely known for its anti-inflammatory and sedative properties. Unlike tetrahydrocannabinol (THC), CBD does not get you high. It also does not have the same euphoric and addictive effects.
Does CBD Work for Sleep Apnea?
Although CBD is not considered a definitive cure for sleep apnea, a lot of people who use CBD oil for sleep apnea claim that it helps them fall asleep faster, improves their sleep quality, and also reduces the number of times they wake up in the middle of the night. More studies are needed to determine whether CBD is truly effective for sleep apnea, but there is enough anecdotal evidence to suggest that it can be used to help reduce sleep apnea symptoms.
In What States is CBD Oil Legal?
The legality of CBD is still a gray area that is open to a lot of interpretation. Those who are in the CBD industry will most likely tell you that for as long as your CBD oil contains less than 0.3% THC, it is considered hemp, and is legal in all U.S. states under the 2014 Farm Bill. This is the legal limit set by the federal government, so for example, if you are from the Big Apple and you are searching for New York cannabis, you’ll probably be fine for as long as you’ll buy a product that contains less than 0.3% THC. To help you better understand the legal implications of using CBD oil, here’s an article that talks about CBD and THC in detail.
How to Take CBD Oil for Sleep Apnea
CBD oil is one of the most commonly used forms of CBD for sleep apnea. You can buy CBD in a variety of forms, such as tinctures, vape pens, edibles, topicals, and even capsules. However, the most popular and effective way to use CBD oil for sleep apnea is to use a sublingual tincture. A sublingual tincture is a tincture that is placed under the tongue and is usually taken before bedtime.
CBD Dosage for Sleep Apnea
There is no FDA guidance on the dosage of CBD oil for sleep apnea. Most people who use CBD oil for sleep apnea suggest that the recommended dosage is 1-2 drops of CBD oil under the tongue before bedtime. As with any other alternative medication, it’s highly recommended to start with the lowest possible dose and gradually increase the dosage over time, depending on how your body responds to CBD oil.
The Limitations of Using CBD for Sleep Apnea
While CBD oil is generally safe for consumption, there are a few things that you should be aware of before using it for sleep apnea. First, it causes minor side effects like fatigue, diarrhea, loss of appetite, dry mouth, and drowsiness. Second, it may react with other medications that you are taking, particularly blood thinners. Lastly, due to the unregulated nature of the CBD oil industry, finding a reputable source of CBD oil for sleep apnea can be a bit challenging.
Dr. Carleara Weiss recommends, “A good tip is checking if the company has a certificate of analysis (COA,) indicating that their product is accurate with everything described in the label.”
Can You Put CBD Oil in a CPAP Machine?
CPAP or Continuous Positive Airway Pressure machine is a device that is used to treat sleep apnea. It works by pushing the air down into the throat and keeping the airway open. CPAP machines are not designed to deliver a therapeutic dose of CBD oil. It is best to ask your sleep apnea doctor about using CBD oil with your CPAP machine. Furthermore, if you are newly diagnosed with sleep apnea syndrome, know that you can avail of Aeroflow Sleep, CPAP supplies through insurance.
How to Choose the Right CBD Oil for Sleep Apnea
As mentioned earlier, the CBD oil industry is still generally unregulated. There is no standardized way to measure the quality of CBD oil for sleep apnea. One way to find the best CBD oil in the market is to look for a reputable company that has a proven track record and a long-list of satisfied customers; like THC Design.
Then, of course, contact us (Aeroflow Sleep) for more information about the sleep apnea therapy that best coincides with your sleep disorder. We work with your insurance provider and primary care doctors to get your CPAP supplies covered up to 100%. We’re even accredited by Medicare and Medicaid. Click below to sleep well and live better.
Need Fresh CPAP Supplies?
From CPAP machines and masks to tubing and filters, Aeroflow Sleep covers your sleep apnea essentials up to 100% through insurance. Plus, you’ll be paired with a dedicated Sleep Specialist, get access to our user-friendly patient portal, and receive world-class resources like our AI mask-fitting technology.
There is a current shortage of CPAP machines nationwide. It is for this reason that Aeroflow Sleep is unable to provide machine replacements at this time.
What You Need To Know About CBD And Sleep
There’s nothing worse than not being able to sleep. You toss and turn, maybe check your phone a few times, and worry as minutes ticks away, leaving with less time to get quality sleep. This might make you try anything to knock yourself out, even CBD oil. However, can CBD and sleep make a difference?
What You Need To Know About CBD And Sleep
First, What Is CBD?
CBD is a naturally occurring compound found in hemp that is separate from THC, the compound found in marijuana that is responsible for causing a high. CBD is not psychoactive and doesn’t get people high, but instead may provide a variety of benefits by positively impacting the endocannabinoid system (ESC).
The ESC is a biological system made up of cannabinoid receptors throughout the body. It’s responsible for regulating normal bodily functions such as appetite, mood, sleep, digestion, pain, and more. When CBD interacts with these receptors they may provide relief from insomnia, nausea, chronic issues, and more.
IS CBD Legal? Yes, CBD is federally legal and many states are passing individual laws on CBD sales and regulation. In most states, it’s legal to purchase CBD oil with less than .3% THC, which will not get you high or appear on a drug test.
CBD For Sleep
When it comes to falling asleep CBD may be able to assist be relieving issues that keep you awake. It doesn’t necessarily make you drowsy like sleep medications. For example, CBD may relieve:
Stress and anxiety. When you lay down and can’t clear your mind due to how much you have to do at work or worrying about certain situations over and over it can keep you up. Especially if you’re stressed about getting used to a new CPAP mask. However, CBD may be able to clam your mind and help you remain calm to prevent stress and restore a natural balance. This way you’ll be able to fall asleep instead of staying up to worry.
CBD may also be able to relax your body by reducing pain and inflammation. This way instead of lying awake wishing you could find relief, you could experience soothing relief. It may also prevent pain from waking you up as well. Also, because CBD may be linked to reducing hypertension, so it may have a role in relaxing your body for sleep.
In order to feel rested, aside from treating sleep apnea your body needs to naturally cycle through the sleep stages a few times each night. The stages are 1, 2, 3, and REM (Rapid Eye Movement) and it takes about 90 to 110 to cycle through. For proper rest, your body needs to spend the correct amount of time in each cycle and CBD may help you achieve a more structured sleep.
CBD And Sleep Apnea
There is speculation that CBD may be able to treat the cause of sleep apnea, whereas CPAPS devices help you manage the condition. Obstructive sleep apnea (OSA), the most common type, occurs when the soft tissues of your throat collapse blocking your airways. CPAPs work by providing a constant stream of air to keep your airway clear, allowing you to get the oxygen necessary for proper rest.
The idea that CBD may help you keep your airways open by keeping your muscles relaxed is still being explored, but more studies need to be performed. So far, CBD for sleep has only been researched with the use of THC as well and it did so the potential to possibly provide sleep apnea relief.
THC And Sleep
So if you live in a state where recreational or medical marijuana you may be inclined to try THC for sleep, but a few potential negative side effects have been found. For example, THC may:
- Increase anxiety
- Decrease the amount of time spent in REM sleep for improper rest
- Make you feel drowsy the next day
- Different concentrations may affect your body differently
How To Sleep Better Now
Keep using your CPAP machine to continue managing sleep apnea for better rest. CBD could potentially help by relaxing your airways, but more studies need to be performed to confirm this. In the meantime keep using your CPAP, however, CBD may help you relax and to fall asleep faster. Always ask your doctor before taking or trying new medications.
CBD Oil for Sleep Apnea: How Can It Help?
Sleep apnea refers to a group of breathing disorders such as problems with snoring, headaches, difficulty staying asleep, and lethargy in the daytime.
Although CBD isn’t an established treatment for sleep apnea, many people are using CBD oils and other products to improve their quality of sleep and control the symptoms of sleep apnea.
CBD is the major cannabinoid in hemp plants; it modulates the activity of the endocannabinoid system (ECS), which is the master regulatory network in the body. By interacting with the ECS, CBD can act on several essential functions, including pain, mood, memory, fertility, immune response, appetite, sleep, and more.
Today, we explain how using CBD may help you alleviate the symptoms of sleep apnea — and how to use it to get the most out of your supplementation.
But first, let’s take a closer look at sleep apnea.
What Is Sleep Apnea?
As reported by Mayo Clinic, sleep apnea is a sleeping disorder manifesting as problems with breathing that repeatedly starts and stops.
Sleep apnea can be broken down into three main types, including:
- Central sleep apnea (CSA) – this type of sleep apnea occurs when the brain fails to communicate properly with the muscles responsible for breathing.
- Obstructive sleep apnea (OSA) – is the most common sleep apnea disorder. It occurs upon the relaxation of the throat muscles.
- Complex sleep apnea syndrome – this disorder can be triggered by both types of sleep apnea and is often called treatment-emergent central sleep apnea.
The two common underlying causes of sleep apnea are a person’s physical structure or comorbid conditions, such as:
- Endocrine disorders
- Genetic syndromes
- Heart or kidney failure
- Neuromuscular disorders
- Premature birth
Symptoms of Sleep Apnea
The symptom of apnea include:
- Difficulty focusing
- Decreased sexual drive
- Loud and frequent snoring
- Unrefreshing sleep
- Morning headaches
- Gasping sounds
- Silent pauses when breathing
- Memory loss
- Nocturia (waking up to head to the bathroom at night.
The risk factors for sleep apnea include the following:
- Hypertensive patients
- Middle-age people
- Overweight or obese individuals
- People with large neck sizes
- Individuals with a family history of sleep apnea
Untreated sleep apnea can cause daytime fatigue, cardiovascular problems, metabolic syndrome, type 2 diabetes, and co-deprivation of sleep on the partner’s side (due to loud snoring).
Does CBD Oil Help with Sleep Apnea?
In a study published in the journal Current Neuropharmacology, the authors found that CBD might be the modulator of the sleep-wake cycle.
The National Sleep Foundation states that the sleep-wake cycle, also known as the body clock or circadian rhythm, is the body’s internal system that controls feelings of wakefulness and sleepiness over 24 hours.
A study from the journal Sleep indicates that the circadian system plays an important role in the development of sleep apnea. The research team also suggested that this system could be the therapeutic target in the treatment of sleep apnea.
In 2016, a study was published in the journal Endocrine Reviews, stating that the circadian system influences the body’s sleep-wake cycle. The authors also added that sleep duration is affected by the circadian phase at which sleep occurs.
Research has concluded that the endocannabinoid system (ECS) helps regulate the sleep-wake cycle — suggesting that the lack of restorative sleep could lead to dysregulation within the ECS.
The authors also noted that the ECS becomes engaged in the recovery of sleep after a person suffers from abnormal sleep periods.
Why Are People Turning to CBD for Sleep Apnea
As mentioned earlier, there are no direct studies on the effects of CBD on sleep apnea. That being said, research shows that CBD might be a promising therapeutic agent for this condition — and for the management of its symptoms.
Here’s why people are using CBD for sleep apnea instead of conventional medications.
CBD for Sleep
People with sleep apnea often experience trouble sleeping (insomnia) or go through excessive daytime sleepiness as a result of the imbalance in their circadian rhythm.
In 2017, researchers published a study in the journal Current Psychiatry Reports, highlighting CBD as the potential treatment for insomnia depending on the CBD dose. High doses of CBD had a sleep-inducing effect, while low CBD doses stimulated daily awareness.
Another study found that patients with insomnia who took a high dose of 160 mg of CBD reported increased total sleep time.
The Journal of Clinical Psychopharmacology has also found that low doses of CBD were linked with increased alertness in four males and four females who received 15 mg of CBD.
In a case study published in The Permanente Journal, the researchers have shown that CBD oil administration improved the quality and quantity of the test subject’s sleep. The patient also reported reduced anxiety.
Another study from the Journal of Psychopharmacology found that rats who were given CBD exhibited increased sleep time overall.
CBD can also help with snoring. Although there are no studies that would examine CBD’s efficacy in this condition, there are studies on its potential effects on the conditions that cause snoring.
A study published in The American Review of Respiratory Disease concluded that heavy snorers experience more intense snoring during slow-wave rapid eye movement (REM) sleep.
A research paper from the journal FEBS Letters found that CBD might reduce REM sleep. This animal-based study also found that CBD might increase daytime wakefulness.
However, the authors didn’t draw a clear line between CBD, sleep apnea, and snoring.
CBD for Blood Pressure
Sleep apnea patients are prone to developing high blood pressure also known as hypertension.
A 2017 study released in the journal JCI Insight showed that a single dose of CBD reduced blood pressure in healthy participants.
9 males took a dose of 600 mg of pure CBD. The research team suggested that CBD may affect cardiovascular disorders. They have yet to study these properties in sleep apnea patients who have hypertension.
A 2017 review of the existing studies on CBD’s effects on the dynamics of blood flow found that CBD might be useful for treating several cardiovascular disorders, including myocardial infarction, hypertension, and strokes.
CBD for Anxiety and Depression
A 2019 study reported that the frequency of anxiety and depression was higher in patients with sleep apnea than in most individuals.
The Permanente Journal published a research paper revealing that CBD had a calming and balancing effect on the central nervous system. 22 adult subjects with anxiety and sleep disorders reported that their conditions improved after taking CBD.
In a 2019 study posted in the journal Frontiers in Psychology, the authors stated that CBD might curb anxiety-like behaviors. The study tested 37 patients with social anxiety; all subjects reported that their anxiety significantly dropped after a dose of 300 mg of CBD oil.
Other studies have brought similar results, suggesting that CBD had anxiolytic and antidepressant properties.
CBD for Headaches
Sleep apnea patients regularly suffer from headaches. They are typically woken up by these headaches resulting in the person feeling unrefreshed even after a full night’s sleep.
Headaches involve mild to moderate pain, typically in the neck or at one side of the head.
A 2020 study from the journal Frontiers in Pharmacology pointed to CBD as a promising treatment for chronic pain and headaches.
In another study — conducted in 2018 — researchers tested 7 kidney transplant patients. The subjects first took 100 mg of CBD twice a day for 3 weeks. The dosage was steadily increased by 150 mg throughout the study’s duration.
Two patients reported total pain relief, while four experienced a partial response in the first two weeks. Meanwhile, one patient reported no signs of relief.
The authors of the study concluded that CBD could be a safe and well-tolerated treatment for headaches.
In 2020, the journal Current Pharmaceutical Biotechnology released a study that found a CBD topical formulation to be effective for symptomatic relief of peripheral neuropathy of the lower body parts.
The study involved 29 patients with peripheral neuropathy. They reported that the topical formulation reduced severe pain, cold, and itchiness in the problematic spots.
CBD for Diabetes
Sleep apnea was linked to type 2 diabetes in a 2016 study. Type 2 diabetes is a condition occurring when a person’s blood sugar is too high and the body can’t use it for energy — it’s the most common type of diabetes.
In a study published in the Journal of the American College of Cardiology, the researchers noted that CBD has positive effects on diabetes. The study highlighted the antioxidant, neuroprotective, and anti-inflammatory properties of CBD.
A combination of CBD and THCV (tetrahydrocannabivarin) helped reduce blood glucose levels and increase insulin production in type 2 diabetes patients in a study published in 2016 by the journal Diabetes Care.
Why Use CBD Oil for Sleep Apnea?
- CBD has demonstrated potential benefits for the symptoms of sleep apnea in animal and human studies, as well as in clinical trials despite not being an established treatment.
- CBD has a great safety profile. You can use it without the risk of dangerous side effects, lethal overdose, or addiction.
- CBD is legal in all 50 states and can be purchased over the counter. You don’t need a prescription for hemp-derived CBD products.
- CBD can influence our circadian system, which is a potential therapeutic target for sleep apnea.
The Limitations of Using CBD for Sleep Apnea
- There are no direct studies that would investigate CBD’s efficacy for sleep apnea.
- CBD still has a few mild side effects, such as tiredness, diarrhea, and changes in appetite.
- The FDA hasn’t approved the use of CBD for treating medical conditions other than epilepsy. Therefore, there are no standard dosage guidelines or regulations surrounding the quality of CBD products.
- The above situation creates room for mislabeled products. According to different studies, 26% of tested samples contained less CBD than advertised, and 21% had THC amounts that were large enough to get children high.
How to Choose the Right CBD Oil for Sleep Apnea?
People generally prefer the full-spectrum type of CBD for sleep apnea. This type uses all the ingredients occurring in the Cannabis sativa plant, such as CBD, adjunctive cannabinoids, terpenes, flavonoids, fatty acids, essential oils, and traces of THC.
All these compounds work together in synergy to boost the therapeutic effects of the plant. Scientists call this mechanism the entourage effect.
If for some reason, you don’t want to take any THC in your CBD oil, you can opt for a broad-spectrum version of CBD, which comes with the same range of phytonutrients, save for THC.
People who are allergic to certain hemp compounds turn to CBD isolates. This is the purest version of CBD; it has no odor and flavor and provides the highest dose of CBD per serving.
Unfortunately, isolate-based CBD oils don’t leverage the concept of the entourage effect, which makes them a less desired option among users.
You should also check your vendor’s reputation, the source of CBD, extraction method, and third-party testing before buying any CBD product for sleep apnea.
CBD Dosage for Sleep Apnea
Due to the lack of FDA guidelines, CBD has no standard dosage recommendations. If you want to figure out the best CBD dosage for you, then you should increase the amount of CBD oil intake gradually. Patients with sleep apnea are encouraged to start with a low amount and gradually work their way up to the dosage when they reap the most benefits without adverse reactions.
As mentioned before, high doses of CBD might act as sedatives, while low doses might promote alertness.
It’s a good idea to write down how you feel after each dose of CBD so that you can monitor the effects and adjust the dosage accordingly.
If you have sleep apnea and are considering adding CBD to your daily routine, it’s best to consult a doctor. Properly treated sleep apnea by a qualified professional is important to protect you against long-term complications.
How to Take CBD Oil for Sleep Apnea?
There are several forms of CBD you may take that are available on the market that you can use for sleep apnea. However, some CBD types may be more effective than others.
CBD oils are the most common format. They are taken under the tongue for improved absorption. Patients can place the oil using a dropper attached to the bottle and hold it beneath the tongue for about 60 seconds before swallowing.
There are also CBD vape pens available in the market today that offer higher bioavailability than oils; they also have a faster onset, but on the other hand, their effects are shorter-lived.
CBD also comes in oral formats, such as capsules and edibles. These products provide a fixed dose of CBD per serving, so there is no guesswork involved — you just eat your favorite CBD-infused gummies or take as many CBD capsules to help you sleep as recommended by your doctor, or as stated on the jar.
Finally, there are CBD topical formulations that you can use as a means of localized relief from pain, irritation, redness, swelling, and other kinds of physical discomfort.
Key Takeaways on Using CBD Oil for Sleep Apnea
CBD has demonstrated several health benefits for patients with sleep apnea. Both animal and human studies suggest that this cannabinoid can be used for symptom control and to improve sleep quality in people suffering from this condition.
On top of that, CBD might be useful in regulating a person’s sleep-wake cycle — one of the main therapeutic targets for sleep apnea.
More research needs to be done on the link between CBD and sleep apnea, but current findings are very promising.
You can incorporate CBD oil into your daily routine to reduce anxiety, hypertension, pain, and type 2 diabetes, all of which are the side effects of untreated sleep apnea.
CBD may be used safely as adjunctive therapy to some conventional sleep apnea treatments, such as lifestyle changes, physical activity, CPAP machine use, and diet modifications.
Do you take CBD oil for sleep apnea? Does it help? Let us know by leaving a comment below:
- Murillo-Rodríguez, E., Sarro-Ramírez, A., Sánchez, D., Mijangos-Moreno, S., Tejeda-Padrón, A., Poot-Aké, A., Guzmán, K., Pacheco-Pantoja, E., & Arias-Carrión, O. (2014). Potential effects of cannabidiol as a wake-promoting agent. Current neuropharmacology, 12(3), 269–272.
- Butler, M. P., Smales, C., Wu, H., Hussain, M. V., Mohamed, Y. A., Morimoto, M., & Shea, S. A. (2015). The Circadian System Contributes to Apnea Lengthening across the Night in Obstructive Sleep Apnea. Sleep, 38(11), 1793–1801. (2)
- Morris, C. J., Aeschbach, D., & Scheer, F. A. (2012). The circadian system, sleep, and endocrinology. Molecular and cellular endocrinology, 349(1), 91–104.
- Babson, K. A., Sottile, J., & Morabito, D. (2017). Cannabis, Cannabinoids, and Sleep: a Review of the Literature. Current psychiatry reports, 19(4), 23. (4)
- Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente journal, 23, 18–041.
- Chagas, M. H., Crippa, J. A., Zuardi, A. W., Hallak, J. E., Machado-de-Sousa, J. P., Hirotsu, C., Maia, L., Tufik, S., & Andersen, M. L. (2013). Effects of acute systemic administration of cannabidiol on sleep-wake cycle in rats. Journal of psychopharmacology (Oxford, England), 27(3), 312–316.
- Shannon, S., & Opila-Lehman, J. (2016). Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report. The Permanente journal, 20(4), 16-005.
- Monti J. M. (1977). Hypnoticlike effects of cannabidiol in the rat. Psychopharmacology, 55(3), 263–265.
- Shahveisi, K., Jalali, A., Moloudi, M. R., Moradi, S., Maroufi, A., & Khazaie, H. (2018). Sleep Architecture in Patients With Primary Snoring and Obstructive Sleep Apnea. Basic and clinical neuroscience, 9(2), 147–156. (9)
- Murillo-Rodríguez, E., Millán-Aldaco, D., Palomero-Rivero, M., Mechoulam, R., & Drucker-Colín, R. (2006). Cannabidiol, a constituent of Cannabis sativa, modulates sleep in rats. FEBS letters, 580(18), 4337–4345.
- Jadoon, K. A., Tan, G. D., & O’Sullivan, S. E. (2017). A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study. JCI insight, 2(12), e93760.
- Sultan, S. R., Millar, S. A., England, T. J., & O’Sullivan, S. E. (2017). A Systematic Review and Meta-Analysis of the Haemodynamic Effects of Cannabidiol. Frontiers in pharmacology, 8, 81.
- Kim, J. Y., Ko, I., & Kim, D. K. (2019). Association of Obstructive Sleep Apnea With the Risk of Affective Disorders. JAMA otolaryngology– head & neck surgery, 145(11), 1020–1026.
- Shannon, S., Lewis, N., Lee, H., & Hughes, S. (2019). Cannabidiol in Anxiety and Sleep: A Large Case Series. The Permanente journal, 23, 18–041.
- Masataka N. (2019). Anxiolytic Effects of Repeated Cannabidiol Treatment in Teenagers With Social Anxiety Disorders. Frontiers in psychology, 10, 2466.
- Argueta, D. A., Ventura, C. M., Kiven, S., Sagi, V., & Gupta, K. (2020). A Balanced Approach for Cannabidiol Use in Chronic Pain. Frontiers in pharmacology, 11, 561.
- Cuñetti, L., Manzo, L., Peyraube, R., Arnaiz, J., Curi, L., & Orihuela, S. (2018). Chronic Pain Treatment With Cannabidiol in Kidney Transplant Patients in Uruguay. Transplantation Proceedings, 50(2), 461–464.
- Xu, D. H., Cullen, B. D., Tang, M., & Fang, Y. (2020). The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities. Current pharmaceutical biotechnology, 21(5), 390–402.
- Grandner, M. A., Seixas, A., Shetty, S., & Shenoy, S. (2016). Sleep Duration and Diabetes Risk: Population Trends and Potential Mechanisms. Current diabetes reports, 16(11), 106.
- Rajesh, M., Mukhopadhyay, P., Bátkai, S., Patel, V., Saito, K., Matsumoto, S., Kashiwaya, Y., Horváth, B., Mukhopadhyay, B., Becker, L., Haskó, G., Liaudet, L., Wink, D. A., Veves, A., Mechoulam, R., & Pacher, P. (2010). Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. Journal of the American College of Cardiology, 56(25), 2115–2125.
- Jadoon, K. A., Ratcliffe, S. H., Barrett, D. A., Thomas, E. L., Stott, C., Bell, J. D., O’Sullivan, S. E., & Tan, G. D. (2016). Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study. Diabetes care, 39(10), 1777–1786.
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.