7 Brands For Comfort, Relief & Relaxation. CBD oil is a popular natural solution for many types of aches and pains. In this guide, we cover the top 5 CBD oil brands for pain and explain how this supplement can help with your condition. Scientists have tested CBD’s efficacy as an analgesic—and with promising results. Here’s what we know so far about how we can use CBD oil for pain relief.
Best CBD Oil For Pain in 2022 – 7 Brands For Comfort, Relief & Relaxation
Having acute or chronic pain can be extremely debilitating. Without the ability to effectively manage pain, many people find themselves unable to work, enjoy hobbies or even take care of their basic needs. But effective pain management doesn’t work the same for everyone. For some people, traditional pain medications simply don’t work well while others can’t take them because of medical conditions like liver disease. And over-the-counter painkillers come with their own serious risks, like gastrointestinal bleeding.
So, what’s a person with pain supposed to do? For many, the answer is CBD oil.
A natural remedy for pain, CBD oil is extracted from the hemp cannabis plant. Unlike marijuana, it doesn’t contain THC (tetrahydrocannabinol), the psychoactive compound that produces the “high” associated with cannabis use. CBD oil for pain relief is available in a variety of forms, including tinctures, capsules, edibles, and topical creams. But to get the most effective wellness relief, it’s important to choose the right product made with the best practices. To ensure your CBD oil meets your needs and is of the highest quality, we’ve created this list of the best CBD oil for pain relief.
7 Best CBD Oil for Pain – Quick Summary
- CBDfx– Editor’s Choice – Best CBD Oil for Pain
- CBDistillery – Runner up
- Green Roads – Honorable Mention
- CBD American Shaman – Staff Pick
- Sunday Scaries – Good Performer
- Secret Nature – Specialized
- Extract Labs – Budget Friendly
CBD Oil for Pain: Top 7 Brands Reviewed
1. CBDfx – Editor’s Choice – Best CBD Oil for Pain
- Potent CBD concentrations
- Multiple discounts available for first-time buyers
- Multi-cannabinoid psilocybin formulas
- Gluten-free product line
- No isolate options
CBDfx is a globally recognized CBD brand with a mission to provide the highest quality CBD products on the market. Their CBD oil is derived from organically grown hemp plants and is free of harmful pesticides and herbicides. With a commitment to quality and safety, all of their products are third-party lab tested for potency and contaminants.
CBDfx offers a wide range of CBD oils in different strengths and flavors. They also sell a variety of CBD-infused topicals, gummies, vape pens, and more.
CBDfx CBD Oil for Pain
The company’s most popular CBD formula is a broad-spectrum wellness tincture that combines the power of CBD with highly sought-after supplements to support a healthy lifestyle. Each 30ml bottle contains CBG, CoQ10, curcumin, and a rich terpene profile in addition to potent CO2-extracted CBD oil. Available in concentrations ranging from 500 to 6000 mg of CBD, this oil can be taken orally or added to food and beverages.
In addition to CBD and non-psychoactive cannabinoid formulas, CBDfx also offers a range of other CBD oils containing active ingredients like melatonin, CBN, THC, and even psilocybin.
Those who prefer a more accurate dosing method can opt for CBDfx’s potent CBD extract in their CBD gummies, capsules, vape liquids, and even topicals.
Why We Like CBDfx
CBDfx made the top of our list because its wide product line is specially designed to help manage pain by offering comprehensive wellness support solutions. So whether your acute or chronic pain condition is sleep-related, emotionally triggered, a result of arthritis pain or just plain old muscle soreness, CBDfx has a product that can help.
2. CBDistillery – Runner Up
- Easy to navigate website
- CBD oil manufactured in a cGMP-certified facility
- Hemp Authority certified
- 37K+ 5-star reviews
- Tincture only available in full-spectrum CBD oil
- Not all products available for international shipping
In business since 2016, CBDistillery is one of the most well-known and respected brands in the CBD industry. They are a vertically integrated company, meaning they oversee every step of the production process from seed to sale. Entirely focused on safety and quality, all of the products manufactured by CBDistillery are cruelty-free, non-GMO, and third-party lab-tested.
CBDistillery CBD Oil for Pain
CBDistillery’s most popular CBD oil for pain management is its full-spectrum CBD oil tincture. Available in concentrations of 500-5000mg of CBD, each 30ml bottle comes with a dropper for convenient dosing directly under the tongue or into food and beverages. Full-spectrum CBD oil from CBDistillery also includes a carrier oil (fractionated coconut oil) to enhance absorption and bioavailability.
Those needing wellness support for pain occurring during bedtime hours may want to try CBDistillery’s CBD oils designed for sleep. Containing CBD, CBN and a rich terpene profile, these oils are designed to stimulate the endocannabinoid system for improved pain relief and sleep quality.
Why We Like CBDistillery
Potent full-spectrum CBD oil products that are reasonably priced and backed by a company with an excellent reputation are the reasons CBDistillery made it to such a favorable spot on our list. While they may not have the range of CBD oils of other brands, they do offer several unique CBD oil products like a sleep tincture and CBN oil that are made with high-quality ingredients and backed by third-party lab testing.
3. Green Roads – Honorable Mention
- Multiple CBD oil flavors are available
- Full and broad-spectrum formulas are available
- Choose CBD oil formula based on pain level
- Pharmacist formulated
- More expensive than other brands on this list
About Green Roads
Green Roads is only interested in creating potent CBD products that actually help people. With an in-house team of pharmacists helping to formulate their products, all of the CBD oils from Green Roads are designed to be effective for specific purposes. Additionally, all Green Roads products are third-party lab tested for quality and safety.
Green Roads CBD Oil for Pain
New and experienced CBD users will find the perfect CBD oil for their needs with Green Roads. The site is divided by category and pain level to make choosing the right product as easy as possible.
The most popular CBD oil for pain relief at Green Roads is their full-spectrum CBD oil. Containing 1500mg of CBD (50mg per serving), this product is often chosen by those experiencing moderate to severe pain. Vegan and gluten-free, this potent full-spectrum CBD oil can be taken day or night to provide pain management support for conditions like general muscle soreness and chronic issues like arthritis pain.
Those who prefer a THC-free option as part of their pain management or wellness routines can opt for Green Roads’ many broad-spectrum CBD oil formulas available in Kiwi Apple, Mint, and Citrus flavors.
To target specific spots of soreness, pain, and inflammation without using CBD oil tincture drops, Green Roads has numerous other CBD supplements to relieve pain including CBD creams, lotions, salves, and balms.
Why We Like Green Roads
Green Roads has a prominent spot on our list because of their pain-specific CBD oil choices and excellent informational resources that help users choose the right product for their needs. With science-backed formulas and products that can meet a wide variety of pain management needs, Green Roads is a solid choice for those looking for an effective and trustworthy CBD brand.
4. CBD American Shaman – Staff Pick
- Water-soluble CBD oil formulas
- Made with natural ingredients
- Multiple discounts available
- Only organic, non-GMO hemp used
- Lower CBD potency than others on this list
About CBD American Shaman
CBD American Shaman takes CBD seriously. Making ultra-concentrated, terpene-rich CBD hemp oil extracted from high-quality, all-natural hemp plants, CBD American Shaman is able to bring superior wellness results to those wanting to better manage pain conditions with hemp. Using only organic and non-GMO ingredients, all of CBD American Shaman’s products are designed to be effective and fast-acting. Additionally, their unique water-soluble CBD oil formulas are designed to be more bioavailable and easier for the body to absorb.
CBD American Shaman CBD Oil for Pain
CBD American Shaman offers several ways to take CBD oil as part of a pain management routine. Their most popular CBD oil formula is their line of water-soluble CBD products. Specially formulated to be more bioavailable, water-soluble CBD products from CBD American Shaman are a great choice for those looking for a fast and effective wellness supplement to support pain reduction and relief.
Water-soluble CBD oil formulas from CBD American Shaman are available in regular, extra, and maximum strength with CBD concentrations of 300mg, 450mg, and 900mg, respectively. Furthermore, in addition to a natural hemp flavor, full-spectrum CBD oil from CBD American Shaman comes in cherry, lemon, pina colada, peppermint, hot cocoa, and more.
Those seeking alternatives to CBD oil for pain relieving benefits can also purchase CBD supplements from CBD American Shaman in other forms such as CBD topicals, edibles, capsules, and smokable flower.
Why We Like CBD American Shaman
CBD American Shaman is a staff favorite due to its range of CBD oil flavors that help mask the earthy taste of CBD oils. Additionally, with water-soluble formulas that work to make CBD oil more bioavailable, CBD American Shaman’s CBD products are a great choice for those seeking an effective way to experience the potential benefits of CBD faster and with longer-lasting effects.
5. Sunday Scaries – Good Performer
- Vitamin-enriched CBD oil formula
- Kosher certified
- Made in ISO-certified labs
- Limited product line
- No full-spectrum products available
About Sunday Scaries
With mental stress being a significant cause of a lot of the physical pain we feel, it can often be necessary to target both the mind and body when seeking relief. CBD oils from Sunday Scaries are designed to do just that by providing a broad-spectrum CBD oil formula enhanced with vitamins B12 and D3. With an understanding of this fact, Sunday Scaries has created a CBD product line to help manage mental health and, by extension, alleviate physical pain.
Sunday Scaries CBD Oil for Pain
Sunday Scaries CBD oil is designed to help users achieve a more relaxed state of mind while relieving various forms of physical pain. Formulated with full-spectrum CBD oil and enhanced with vitamins B12 and D3, Sunday Scaries CBD oil is a great choice for those seeking a natural way to support mental and physical wellbeing.
CBD oil from Sunday Scaries contains 500mg of fruit punch flavored broad-spectrum CBD oil. To ensure that the quality of their products meets the highest standards, Sunday Scaries CBD oil is made in ISO-certified labs and is third-party lab tested.
Those looking to boost the potential benefits of Sunday Scaries CBD oil can also purchase the company’s high-quality CBD oil gummies. Made with the same potent broad-spectrum formula, these CBD gummies are available on their own or as part of a discounted CBD wellness bundle.
Why We Like Sunday Scaries
Sunday Scaries made our list thanks to its unique vitamin-enriched CBD oil blend designed to target emotional stress to relieve physical pain. Additionally, with its kosher, vegan, and GMO-free CBD oil products, Sunday Scaries is a great choice for those with specific dietary restrictions or preferences.
6. Secret Nature – Specialized
- UV-proof bottles for longer freshness
- 100% organic
- 2mg of CBD per drop
- Limited tincture availability due to high demand
About Secret Nature
Artisanal wellness support for pain and related conditions is the focus of Secret Nature, a CBD company that only sources its CBD from the finest organic hemp farms in America. In addition to being free of herbicides, pesticides, and other harmful chemicals, all of the hemp used in Secret Nature’s CBD products is also non-GMO.
Secret Nature CBD Oil for Pain
Rather than spread its CBD offerings thin, Secret Nature has focused on creating a small selection of high-quality CBD products, including a potent CBD oil tincture.
Formulated with 1500mg of CBD in each bottle, Secret Nature’s CBD oil contains a whopping 2mg of CBD per drop. In addition to the potent hemp CBD extract in their oils, Secret Nature adds organic coconut oil, black seed oil, and Shilajit oil as a natural source of MCTs to further enhance the bioavailability of their CBD oil.
Furthermore, all of Secret Nature’s CBD oils are stored in UV-proof bottles to ensure their CBD products maintain peak freshness.
Why We Like Secret Nature
We really like the positive reviews customers have left about their experience with Secret Nature. From better overall wellness to reduced pain and inflammation, it is clear that those who have tried Secret Nature’s CBD oil are big fans. Additionally, with such a potent CBD oil tincture available, Secret Nature is a great choice for those seeking maximum relief from their CBD products.
7. Extract Labs – Budget Friendly
- Multiple types of CBD products (broad-spectrum, full-spectrum, CBD isolate)
- Veteran owned
- Certified organic
- Leaping Bunny Certified for cruelty-free manufacturing practices
- Returned orders may be subject to a 25% restocking fee
About Extract Labs
Founded by a combat veteran interested in the potential benefits of hemp cannabis plant extracts for a variety of wellness results, Extract Labs is a CBD company that takes an innovative and sustainable approach to CBD production. By partnering with Colorado State University, Extract Labs is able to utilize cutting-edge technology and equipment to create some of the most potent CBD products on the market.
Moreover, all of Extract Labs CBD is produced from 100% certified organic Colorado-grown hemp and is lab tested for purity and potency by a third party.
Extract Labs CBD Oil for Pain
Extract Labs knows that not all supplemental wellness solutions for pain management can or should be the same. That’s why they offer CBD oil in multiple cannabinoid profiles to ensure first-time and experienced CBD users get exactly what they need to meet daily or acute pain management needs.
Their most popular product is a raspberry flavored full-spectrum CBD oil. Available in 1000 and 2000mg concentrations, this CBD oil is a great choice for those who prefer natural fruit flavoring and the potential benefits of taking CBD oil with other hemp-derived cannabinoids and terpenes.
For those interested in a non-THC solution to help supplement their pain management wellness routines, Extract Labs CBD isolate formula contains nothing but 1000mg of pure CBD.
To combine pain management with other wellness support, Extract labs offers concentrated oil tinctures containing CBC, CBN, CBG, and CBDa to support a healthy immune system in addition to support for relief of pain symptoms.
Why We Like Extract Labs
As a veteran-owned CBD company, we’re big fans of Extract Labs and their commitment to using only the highest quality ingredients in all of their CBD products. We also like that they provide multiple options for those seeking pain relief with CBD, including full-spectrum and THC-free options.
How Did We Choose Our Top 7 CBD Oils for Pain?
Choosing our selections for the seven best CBD oils for pain started with careful research into the following categories to ensure that each product met our high standards for quality and effectiveness.
- Customer reviews: If customers don’t like it, we won’t recommend it. All of the products on our list have been vetted for customer satisfaction with positive reviews from those who have tried them.
- Hemp source: Organically grown, non-GMO, and pesticide-free hemp is always preferable. We also looked for companies that source their hemp from the United States to support domestic farmers.
- Extraction method: Safe extraction methods free from harsh chemicals or solvents are essential to getting high-quality CBD oil. Therefore, we only considered companies that use CO2, olive oil, or other extraction processes that don’t use harsh solvents.
- Ingredients: Often CBD oil isn’t the only ingredient in hemp extract supplements. For this reason, we only considered CBD brands that use natural ingredients like coconut or hemp seed oil to boost their products’ absorption, efficacy, and quality.
- Lab testing: The CBD industry is largely unregulated. As a result, it’s important to choose brands committed to transparency by voluntarily sending their products for independent lab testing. All of the brands on our list make it easy to find their lab results so you can be confident that you’re getting what you pay for.
What To Consider When Buying CBD Oil for Pain
Purchasing CBD oil to help with pain is something that should be approached with caution and due diligence. Here are a few factors that you should consider when looking for the best CBD oil for your needs.
CBD Content & Potency
The amount of CBD in a product is important, but it’s also important to consider the concentration or potency of each dose. To figure out the amount of each drop, divide the total amount of CBD by the bottle size. That will give you an amount per 1mL dropper. Then divide the drops in a dropper (20 drops) into the amount of CBD per 1mL.
For example, a 1000mg bottle of CBD oil with a 30ml serving size will give you 33.3mg of CBD per dropper, while a 500mg bottle with the same serving size will only give you 16.6mg per dropper. Divided by 20, a 1000mg CBD bottle contains 1.67mg per drop, and a 500mg bottle contains .83mg per drop.
So, when considering the best CBD oil for pain relief, look at the concentration to make sure the dosage has what you need to manage your symptoms.
The type of CBD in a product also matters. There are three main types of CBD on the market: full-spectrum, broad-spectrum, and isolate.
Both full and broad-spectrum CBD oil formulas offer an array of cannabinoids that can interact with cannabinoid receptors in the body to provide a range of potential benefits. The difference between the two is that broad-spectrum CBD oil goes through an additional filtration to remove all detectable traces of THC. So if you are looking for a THC-free product that still contains beneficial phytocannabinoids, flavonoids, and terpenes, consider broad-spectrum over full-spectrum.
NOTE: In the USA, full-spectrum CBD products can contain no more than 0.3% THC. This means that even if you use full-spectrum CBD oil, the THC concentration is so low that you won’t experience any psychoactive high associated with medical and recreational marijuana use.
CBD isolate is the final type of CBD, containing nothing but pure cannabidiol. It’s been stripped of all other cannabinoids, flavonoids, and terpenes, leaving only the CBD molecule. This makes it ideal for those who want to avoid any trace of THC or are looking for the most potent CBD product possible.
CBD products come in a variety of delivery methods, including tinctures, gummies, topicals, vapes, and more. The best delivery method for you will depend on your preferences and how you want to use CBD. For example, those with lung conditions may prefer to use a CBD oil for pain relief to avoid exacerbating breathing issues with a CBD vape.
Those with pain in a specific area may find they prefer their CBD oil in topical solutions that directly target their pain. Gummies and tinctures are popular among those who want a convenient way to take their CBD oil with them on the go.
Reputation & Credibility of CBD Brand
The reputation and credibility of a CBD brand are essential considerations when buying CBD oil for pain relief. Makers of the best CBD oils are transparent about their policies, procedures, and ingredients.
Look for brands that have sent their products for independent lab testing to verify CBD content and rule out the possibility of contaminants. And be sure to check out customer reviews to get an idea of how satisfied other users are with a brand’s products before you make your purchase.
It is also a good idea to check for certifications and awards from leading industry bodies like the US Hemp Authority, cGMP, and ISO. These signify that a brand is adhering to high standards regarding product quality and safety.
What are the Health Benefits of CBD?
Given the concerns surrounding the efficacy of traditional pain medications, in particular the risks associated with opioids, taking natural CBD oil to alleviate pain has been a topic of great interest to individuals and scientists alike. Currently, thousands of studies are examining the effectiveness of CBD and other hemp-derived cannabinoids in treating a variety of medical conditions, such as:
- Chronic pain
- Neurodegenerative disorders
Early research from many studies suggests that CBD and other cannabinoids interact with and stimulate the endocannabinoid system within our bodies. This system is thought to be a series of CB1, CB2, and other receptors that regulate various biological processes like mood, memory, appetite, and pain perception.
So, by using CBD oil to manage painful conditions related to genetic disorders, aging, or intense physical activity, you may also experience other benefits such as:
- Reduced inflammation
- Improved sleep quality
- Reduced anxiety and stress
- Improved mental clarity
Note that not everyone may experience the same benefits of using CBD; age, height, weight, and gender can all play a role in how our bodies process and respond to CBD. What works for one person may not work for another, so it’s important to experiment until you find the right dosage and product for your needs.
How to Use CBD Oil
Using CBD oils for any reason is pretty simple. Most bottles come with a convenient 1mL dropper that makes sublingual dosing or mixing into food and beverages easy. By filling the dropper to the desired amount and then squeezing the liquid under your tongue, you can hold it there for 30-60 seconds before swallowing.
For those who prefer not to put drops of oil under their tongue, CBD oils can also be mixed into food or drinks. Just remember that it may take a little longer to feel the effects because the CBD will have to travel through your digestive system first.
Ultimately the right amount of CBD for your pain management needs will depend on your circumstances. Most find that low doses under 10mg are enough to relieve mild chronic pain, while moderate doses between 10-30mg are better for intense chronic pain. However, some may need up to 100mg or more per day for severe chronic pain.
If you find that you only take CBD when you have pain related to intense physical activity (like work or exercise), you should consider faster-acting CBD forms such as CBD oils or topical creams. These products typically have a faster absorption rate, offering relief more quickly.
How Much CBD Oil Should I Take for Acute or Chronic Pain
If you suffer with chronic pain and regularly use CBD products, you probably understand how hemp-derived cannabinoids affect your body and may want to consider using a higher dose (30-100mg) for times when you experience more severe pain.
It is important to remember that you should match your pain intensity with your dosage size. In other words, don’t take a high dose of CBD just because you think it will work better. Instead, start small and increase as needed until you find the desired effects.
Are There Any Side Effects to CBD?
Even with positive confirmation of general safety from regulatory agencies like WHO, and multiple studies confirming the therapeutic potential of CBD, there are always going to be a small number of people for whom CBD just doesn’t work. CBD is generally considered safe and well-tolerated by most people. But like any other wellness supplement on the market, some side effects may be associated with its use.
The most common side effects reported with CBD are gastrointestinal issues like diarrhea, as well as dizziness, drowsiness, and changes in appetite. However, these side effects are usually mild and temporary, going away on their own after a few days.
Additionally, first-time CBD users may notice dry mouth and changes in their sense of taste. This is thought to be caused by the interaction between CBD and the endocannabinoid system, which helps regulate saliva production.
The good news is that because CBD is considered non-psychoactive, meaning it won’t get you high and there is no risk of side effects common to THC-rich products, such as intense euphoria, paranoia, or cognitive impairment.
CBD Oil for Pain – FAQ
1. Can I use CBD oil to treat inflammation in my hands?
Many people prefer CBD oils to other CBD products because it is one of the fastest-acting forms of CBD. CBD oil is absorbed quickly into the bloodstream, where it can then bind to receptors throughout the body, including in the hands. It is widely believed that this interaction between CBD and the endocannabinoid system can help to reduce inflammation and pain throughout the entire body – including the hands.
If you find that CBD oil isn’t hitting the exact spot you need it to, you can also try using a CBD topical cream that can be applied directly to the hands. The advantage of using a topical product is that you can target the specific area that is causing pain or inflammation, and the CBD will be absorbed directly into the skin for faster relief.
2. How often should I take CBD oil for pain?
The frequency with which you take CBD oil for pain relief will largely depend on the severity of your pain. Most people say that 1-2 doses per day offer the desired relief for mild to moderate pain. However, you may need to increase your dosage or frequency up to 3-4 times per day for more severe pain.
When breaking up your doses, it is best to space them out evenly throughout the day. This will help maintain a consistent level of CBD in your system, offering more long-lasting pain relief.
3. Does CBD oil build up in your system over time?
CBD tolerance is something that can happen in cases when a large amount of CBD is consumed on a daily basis. CBD tolerance can be reset in many ways, including changing the type of CBD product you are taking, stopping consumption for a period of time, or taking a break from CBD every few days. Even with a slightly higher tolerance, the effects of CBD will still be present – it may just take a little longer to notice them.
4. What is the best time of day to take CBD oil for pain?
There is no definite answer about the best time of day to take CBD oil for pain relief. If you need lasting all-day relief from chronic pain, it may be a good idea to take CBD oil in the morning and then again at night. However, taking it right before or after physical activity may be a better option if you only need relief for a few hours. Experimenting with different times of day will help you find what works best for you and your specific needs.
5. Do I need a special type of CBD oil for pain?
No, you do not need a special type of CBD oil for pain relief. However, it is important to ensure that you are using a high-quality product free from contaminants. Many believe that a full spectrum CBD oil containing all of the cannabinoids, terpenes, and other beneficial compounds in hemp plants will offer the most relief. But again, what works for some may not work for others, so you may need to try a few different types before finding the one that works best for you.
Better Health & Wellness with CBD Oil for Pain
With the number of people using CBD oil for pain on the rise, there is a growing body of evidence to support its efficacy. But to get the most out of your CBD regimen, it’s important to know the best places to buy CBD products. By purchasing from reputable vendors using high-quality ingredients, you can be sure that you are getting the best CBD oils that will offer the relief you need.
Remember that even the best CBD oils are not a cure-all, but CBD can be an effective tool in your overall health and wellness arsenal. CBD oils can offer significant relief from pain and inflammation when used properly, with few to no side effects. So if you’re looking for an all-natural way to manage pain, CBD oil may be worth considering.
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Best CBD Oil for Pain Relief & Inflammation: Highest Quality Brands On The Market
Over the past three years, CBD oil has become increasingly popular as a health and wellness supplement.
One of the main reasons people are interested in trying CBD oil is because of its pain-killing benefits. We’ll get into the details of how CBD is suggested to help with pain later, along with some suggestions for the best CBD oils for pain and inflammation.
The ability for CBD to help with pain is a significant advantage over conventional pain management options — which often involve addictive and potentially harmful medications. Instead, this natural supplement has very few side effects and an exceptional safety profile — all without compromising on effectiveness.
But how do you choose the right CBD oil for the job?
This is an important question to ask because the truth of the matter is that not all CBD oils work. Many simply contain too little CBD to be of any help, while others contain harmful contaminants like heavy metals, pesticides, or chemical solvents — all of which could add to the pain you’re already experiencing by damaging the sensitive nerve cells around the body.
We’re going to cover all of this in the article below. You’ll learn how to spot a high-quality CBD oil and how current evidence shows CBD to work inside the body.
This is a big topic, so let’s get started with our list of top-rated CBD oils for pain.
Top 10 Best CBD Oil Brands for Pain Management in 2022
Not sure which CBD oil to buy to help with chronic pain? Before we get into the nitty-gritty of how CBD is suggested to work for pain and inflammation, here’s our top 5 list of CBD oils I’ve used myself for back pain.
We’ll also offer some advice on a few ways you can spot a trustworthy CBD vendor even if they didn’t quite make it onto our list.
I’ve been using CBD for over 5 years now and I’ve stumbled upon some stellar companies with top-notch oils and fly-by-night businesses with oils that can’t simply don’t work.
I have a relatively short list of CBD brands that I fully trust and I want to share my choices with you so you can avoid some of the headaches and disappointment I’ve already endured.
Here are my top 10 CBD oil brands for pain:
1. Royal CBD (Best CBD Oil On The Market)
|Total CBD Content||250 – 2500 mg|
|Available Flavors||Natural, Mint, Vanilla, Berry|
|Potency||8.3 – 83.3 mg/mL|
Get 15% off all Royal CBD products. Use code “CFAH” at checkout.
Why Royal CBD is My Top Pick:
As skeptical as I am towards the majority of new CBD brands, I decided to give Royal CBD a try because I liked the company’s dedication to quality. I love seeing companies that take what they do seriously.
You can tell right away from the color, flavor, and consistency of the oil that you’re dealing with a product well above average.
This oil is cheaper than most of the other premium CBD oils I’ve tried, comes in a full range of potencies, and uses some of the best full-spectrum hemp extracts I’ve ever seen. I’ve heard friends using this brand for quite some time and decided to give it a try for myself — so I ordered a few bottles in different strengths.
After taking the Royal CBD’s 2500mg full-spectrum CBD oil for just over a week, I noticed an improvement in my back pain. There was a time when I had serious problems falling asleep because of the sharp pains in my back that seemed to intensify whenever I laid down to fall asleep. It was a nightmare. I’d lay awake for hours changing positions to try and find a spot that didn’t leave me writhing in discomfort.
With this oil, my experience went far beyond what I expected. Not only did it help ease the pain, but my overall quality of sleep improved. I mean, I didn’t sleep longer but I began to wake up rested and with a clear head.
My favorite combination for this particular oil is the vanilla in the 1000 mg bottle. This is the largest potency option currently offered by Royal CBD and has the best value overall. I took the oil twice per day, once in the morning when I woke up, and again in the evening before bed. One bottle of the 1000 mg CBD oil lasted me about a month.
- Sourced from US-grown organic hemp
- Extracted with supercritical CO2
- Contains the full spectrum of cannabinoids and terpenes
- Available in 4 different strengths
- Up to 2500mg of CBD per bottle
- Lab-tested for potency and purity
- Great natural flavors (no aftertaste and comes in multiple flavor options)
- Free shipping within the USA
- Newer brand on the market that only sells online, no physical presence
2. Gold Bee (Best Organic CBD Oil)
- Premium Colorado-grown hemp
- CO2 extraction
- Contains full-spectrum CBD
- Delicious kiwi flavor
- Sweetened with organic honey
- Lab-tested for potency and purity
- Only one flavored option available
- No high-strength oils (yet)
What I Like About Gold Bee:
I honestly believe Gold Bee makes the best organic CBD products out there. The brand combines premium Colorado-grown hemp with organic honey sourced from the Brazillian Rainforest. While Gold Bee offers a modest selection of oils — with up to 1200 mg of CBD per bottle — the formula is spot-on when it comes to the quality of ingredients. I’m totally not going to complain about the potency, as my back pain and sleep quality got better than with some high-strength oils I’ve tried in the past. Considering the quality of these products, they actually come at a bargain price. If you want to try other formats from Gold Bee, you can choose between its high-strength capsules and CBD-infused honey.
3. CBDPure (Runner Up)
|Total CBD Content||100 – 600 mg|
|Potency||1.6 – 10 mg/mL|
What I Like About CBDPure CBD Oil:
I love how transparent this company is. If I were judging companies solely by their transparency level, CBDPure would have scored the second place, right after Royal CBD. The company provides all the details about each stage of production when making this CBD oil. You can find all the third-party lab test results for each batch on the product page — something we’ve come to expect from any high-quality CBD company.
What really makes this company stand out is its incredible satisfaction guarantee. If you order the product and decide it wasn’t working for you, simply send it back and get a full refund. This satisfaction guarantee extends over 3 whole months — which is about three times longer than the industry average.
I keep a bottle or two of CBDPure oil in my medicine cabinet for achy moments after a run or hike with the kids.
The only real downside to this oil is the potency — which comes in denominations of 1.5, 5, and 10 mg/mL. This is suitable for more minor symptoms, but may not be enough for people with heavy CBD demands.
- Sourced from Colorado-grown organic hemp
- Extracted with supercritical CO2
- Tested for the cannabinoid content and purity in a third-party lab
- Rock-solid 90-day return policy
- Narrow product range
- Low potency
- They don’t ship to every state (i.e. Louisiana, Indiana, Arkansas, Kansas)
|Total CBD Content||300 – 4000 mg|
|Available Flavors||Unflavored, Acai Berry, Orange Creamsicle, Peppermint, Watermelon|
|Potency||10 – 133.3 mg/mL|
What I Like About HempBombs:
I used HempBombs CBD isolate-based hemp oil for quite some time before switching to full-spectrum CBD oil and in my opinion, this is the best brand when it comes to CBD isolates. Their products contain 99% pure CBD and ZERO THC.
Now don’t get me wrong, CBD isolates are great, they offer consistent doses of CBD, contain 0% THC, and are generally cheaper than their full-spectrum counterparts. In most cases, I like using a full-spectrum extract like Royal CBD oil because of something called the entourage effect — which is a concept highlighting the phenomenon where cannabinoids like CBD tend to work better when other hemp-derived compounds are also present.
In isolates, the only cannabinoid present is CBD.
HempBombs CBD oil is available in five different strengths — from 300mg to 4000mg per bottle. The CBD is added in the form of a 99% pure isolate — which means there’s going to be virtually no traceable amounts of any other cannabinoids, including THC, CBC, CBG, or CBN.
You can also buy these oils in different flavors. Hemp Bombs often adds new flavors to the list, but my all-time personal favorite is the Acai berry. It’s not too sweet but adds a really pleasant flavor to the otherwise bland CBD and MCT oil formula.
- Sourced from 100% certified organic hemp from European farms
- Extracted with supercritical CO2
- Completely THC-free
- Tested in third-party laboratories for purity and potency
- Available in 5 separate strengths
- Up to 4000mg of CBD per bottle
- Lacks the synergistic effects from other cannabinoids
- The highest potencies are overkill for most users
- Uses synthetic flavoring agents
|Total CBD Content||250 – 5000 mg|
|Potency||8.3 – 166 mg/mL|
What I Like About CBDistillery:
CBDistillery is now one of the largest CBD companies in North America. The company began in 2016 as a legacy brand for Balanced Health Botanicals.
Over the years, CBDistillery has had the chance to really dial-in its CBD oil formula. The company now sells its CBD oil in two formats — “full-spectrum” and “THC-free.” The THC-free option is great for people who want to benefit from the synergy of CBD and other cannabinoids but without bringing any THC whatsoever into their system.
Even the full-spectrum option contains less than 0.3% THC — which is well below the amount needed to cause any psychoactive effects. These oils are both completely non-psychoactive.
You can choose between five different strengths, starting at 250mg up to 5000mg of CBD per bottle. This covers just about every range of potencies you would ever need. We recommend opting for the higher potency options because they have the best value overall. The higher potency you purchase, the further your dollar gets you.
The more potent options also las the longest because you need smaller amounts of the oil each time to get the desired dose of CBD.
I tried the 1000mg bottle to keep myself calm during the first few months after giving birth to my first son and I must admit it helped me maintain my sanity during that time. I found it to have a remarkable calming effect on the body and mind.
- Available as full-spectrum CBD or pure CBD oil (THC-free)
- 5 strengths to choose from
- Carries up to 33.3 mg of CBD per mL (in the 1000 mg bottle)
- Excellent value CBD oil
- The hemp isn’t certified organic
- No flavor options available
- The company website is clunky and hard to navigate
6. NuLeaf Naturals
|Total CBD Content||240 – 4850 mg|
What I Like About NuLeaf Naturals
Nuleaf Naturals is one of the most popular CBD companies in the United States — most likely related to how long the company has been in the business of selling CBD. Nuleaf naturals were one of the first CBD companies to enter the mainstream market.
Despite the companies longstanding reputation, Nuleaf Naturals only sells one CBD oil. When you go to the website you’ll find a few different options, including a pet oil — but it’s important to understand that these are all the exact same full-spectrum extract, the only difference is the bottle sizes.
We love the simplicity of Nuleaf Naturals product lineup. The oils come with a decent potency of around 48 mg/mL, and just about every bottle size you can imagine. This makes it easy for everybody to find a product that works for them regardless of the budget.
With that said, if you have the cash, we highly recommend getting the larger bottle sizes in order to get the best value for your money.
You can choose between five different sizes:
- Sourced from organic Colorado-grown hemp
- Extracted using supercritical CO2
- Made from a full-spectrum hemp extract
- More expensive than the other brands in this ranking
- Narrow product range
7. Charlotte’s Web
|Total CBD Content||200 – 1800 mg|
|Available Flavors||Mint Chocolate, Lemon Twist, Orange Blossom, Olive Oil|
|Potency||7 – 60 mg/mL|
About Charlotte’s Web:
Charlotte’s Web is one of the pioneers in the American CBD industry. Established by the Stanley Brothers, the company has coined a reputation of a trustworthy manufacturer by helping now late Charlotte Figi with her treatment-resistant epilepsy. Although the company has recently received a warning letter from the FDA due to their health claims, they still have many faithful customers and a massive number of positive reviews on the web.
Charlotte’s Web CBD oil comes in several potencies: 200 mg, 500 mg, 1500 mg, and 1800 mg of CBD per bottle. The highest strength offers 60 mg of full-spectrum CBD per milliliter. There are two bottle sizes to choose from: 30 mL and 100 mL; Charlotte’s Web also has flavored variants of its CBD oil, including Lemon Twist, Orange Blossom, Mint Chocolate, and Olive Oil.
What could the company do better?
First off, they could change their extraction method because they use ethanol, which is less efficient than CO2 extraction. Secondly, and most importantly, the suspension in olive oil makes them taste a bit bitter — even in the flavored versions.
- One of the most reputable brands on the market
- Full-spectrum CBD
- Delicious flavored versions
- Up to 1800 mg of CBD per bottle
- Available in two sizes: 30 mL and 100 mL
- Third-party tested for potency and purity
- Non-organic hemp
- Ethanol extraction
- Suspension in olive oil (bitter taste)
- The company received a warning letter from the FDA in the past due to inappropriate health claims
|Total CBD Content||300 – 7500 mg|
|Available Flavors||Natural, Berry, Orange, Mint|
|Potency||10 – 250 mg/mL|
cbdMD is another popular manufacturer that offers a wide range of CBD extracts, from tinctures to gummies to capsules, bath bombs, topicals, sleep aids, and pet products.
The brand offers a wide range of pure CBD oils, with up to 7500 mg of CBD per bottle. The highest potency comes with a whopping dose of 200 mg of pure CBD suspended in MCT oil for higher bioavailability and a smoother flavor. cbdMD also has three flavored CBD oils: Berry, Orange, and Mint.
Despite an impressive potency range, cbdMD uses broad-spectrum CBD in their products, which doesn’t evoke the full entourage effect. The higher potency may not necessarily mean better results in this case.
The company has high transparency standards; not only does cbdMD broadly describe their activity from farming to testing, but they also provide batch-specific certificates of analysis for their products, including the results for potency and common contaminants like pesticides, heavy metals, and residual solvents.
- US-grown, non-GMO hemp
- CO2 extraction
- Up to 7500 mg of CBD per bottle
- Batch-specific certificates of analysis
- Limited entourage effect due to the lack of THC
- Most people don’t need such high doses of CBD in their routine
|Total CBD Content||500 – 3000 mg|
|Available Flavors||Natural, Citrus, Mint Chocolate|
|Potency||16 – 100 mg/mL|
Medterra is a small craft company from California. The brand offers premium CBD oils in different spectra: full-spectrum CBD, broad-spectrum CBD, and isolates. The potency of these products ranges between 500 mg and 3000 mg of CBD per bottle, which is a standard range. On top of the unflavored version, there are two flavored options: Citrus and Chocolate
Medterra prides itself on making the real full-spectrum CBD because each bottle of its full-spectrum CBD oil comes with 2 mg of THC. However, these products are only legal in the states that have legalized higher amounts of THC for recreational use. So, if you want to buy the company’s products in all 50 states, your options are limited to broad-spectrum CBD and CBD isolate. These provide more CBD per bottle — upwards of 1000 mg.
The entire Medterra’s product range is tested in a third-party laboratory for their CBD content and safety.
- Premium-grade CBD oils
- Up to 3000 mg of CBD per bottle
- Available as full-spectrum CBD, broad-spectrum CBD, and isolates
- Lab tested for potency and purity
- The “real” full-spectrum CBD oil isn’t available in all states
- Some of the lab reports indicate higher CBD levels than stated on the bottle
- No discounts for returning customers
10. Joy Organics
|Total CBD Content||450 – 900 mg|
|Available Flavors||Tranquil Mint, Fresh Lime, Summer Lemon|
|Potency||15 – 30 mg/mL|
About Joy Organics:
Joy Organics holds the reputation of one of the most reputable CBD vendors in the industry. The company was established by a woman named Joy Smith, who has been using CBD oil to manage her problems with pain and sleep. After experiencing the benefits of CBD first-hand, she has decided to share her passion for cannabis with other health-conscious consumers.
The brand sells a range of broad-spectrum CBD products from certified organic hemp. They have many positive reviews all over the Internet; they also haven’t received any warning letter regarding health claims from the FDA — unlike many companies in this space (even the veterans like Charlotte’s Web).
The Joy Organics CBD oil features a broad-spectrum CBD formula in a modest potency range, from 450 to 900 mg of CBD per bottle. You can choose from three refreshing flavors: Summer Lemon, Fresh Lime, and Tranquil Mint. The strongest version of the Joy Organics CBD oil contains 30 mg of broad-spectrum CBD in every milliliter, which is a standard dose for most people who take CBD oil for daily supplementation.
In 2018, one of the company’s flavored CBD oils was found to contain a fungicide that is commonly sprayed on citrus fruit during independent lab testing. Fortunately, Joy Organics recalled the product shortly after this incident and implemented a new third-party testing system to make sure there are no flaws in the end product.
- Non-GMO, US-grown hemp
- Supercritical CO2 extraction
- Broad-spectrum CBD
- Delicious flavors
- A bit expensive
- No high-strength oils
CBD Oil for Pain Management: Complete Guide for Beginners
Now that we’ve covered a few CBD oil options that are going to provide the best value for your money, let’s discuss how CBD is suggested to support chronic pain in the first place. We’ll also cover some of the most common ways people are using CBD oil for pain.
What is CBD Oil?
CBD stands for cannabidiol _ it’s one of the primary active ingredients in the cannabis plant. It’s completely non-psychoactive and offers a wide range of benefits to the human body.
CBD oil is a combination of a CBD extract, with a carrier oil to help dissolve and store the CBD. Most CBD oils use carrier oils like MCT oil, or hemp seed oil — which is then combined with CBD isolate, or full-spectrum hemp extract rich in CBD and other similar cannabinoids.
Cannabinoids like CBD are fat-soluble — which means they dissolve when mixed with oil, but won’t dissolve in water. By dissolving these compounds in an oil solution, the CBD becomes much easier to store and use. Instead of measuring out micrograms of CBD crystals or hemp resin, all you need to do is measure oil to get your dose of CBD. This can be done using a simple dropper that comes standard with most CBD oils.
Because of their ease of use, and long shelf-life, CBD oils have become the go-to method of using CBD and other hemp extracts.
You can also opt-out to use CBD-infused gummies if you wanted something discreetly, read our in-depth review on CBD Gummies to understand better.
How Does CBD Work?
Cannabis has been used for managing pain and inflammation for thousands of years.
The earliest records of the medical use of the herb date back to ancient China when the emperor Shen-Nung placed it among other therapeutic substances in the Chinese pharmacopeia (1). The leaves were wrapped around an injury as a poultice to reduce pain and discomfort, and reverse swelling and bruising.
Despite being a known medicine for a long time, scientists have only recently begun to unlock the mechanisms cannabis uses to achieve its important pain-killing benefits.
Since the discovery of the endocannabinoid system in 1992, CBD and other phytocannabinoids have been in the spotlight of modern medicine.
The endocannabinoid system is one of the most important neurochemical networks in the human body (2). It works by interacting with the endocannabinoid system — a series of hormones and receptors that help regulate over a dozen core processes in the human body. The active compounds in the cannabis plant are very similar to the naturally-produced hormones involved with our endocannabinoid system.
By interacting with the endocannabinoid system, CBD and other cannabinoids are able to modulate several key processes, such as:
- Immune function
- Sensory perception (including pain)
- Reproductive health
- Nerve function
How Can CBD Reduce Pain Transmission?
How does all of this relate to pain? The answer lies in the way pain is transmitted to the brain.
When we injure ourselves, cells in the immediate vicinity begin releasing compounds that trigger a cascade of inflammation and sensory activation — which is what triggers the pain transmission.
The pain signal is then sent to the spinal cord through a network of nerves distributed all around the body.
Once in the spine, the pain signal is sent through a gateway (opioid and vanilloid receptors) designed to limit the amount of signal that ends up in the brain for processing. This works like a border crossing. The border security decides whether or not you’re allowed to enter and what you can take with you.
In the context of pain, these gateways can limit the amount of pain signal that continues across the border to the brain. If more pain signal is allowed to pass, the brain perceives more pain. If the pain is stopped at the border, the brain perceives less pain.
Conventional pain medications work by activating the opioid receptors acting as a key gateway for pain transmission to the brain.
CBD has a similar effect, but through a different receptor is known as the vanilloid receptors. These vanilloid receptors are tasked with regulating a specific form of pain caused by either heat or inflammation. CBD has been reported to modulate this vanilloid receptor — leading to a reduction in the pain signals sent to the brain from inflammatory causes such as arthritis, muscle damage, or infection, to name a few.
CBD has other ways it can limit pain transmission as well:
- CBD may reduce inflammation, limiting the initial cause of pain in the body
- CBD acts as an antioxidant, helping the body resist and recover from damage
- CBD relaxes muscle fibers, reducing pain caused by muscle spasms and tightness
More research is needed to fully understand how CBD and other active cannabinoids can block pain. Every year dozens of new research papers are published in an attempt to paint a clear picture of how CBD works, how to get the most benefit from the supplement, and what its limitations are.
(Pain Transmission Pathway to the Brain)
Choosing CBD Oil Companies: How to Differentiate the Good From the Bad
CBD has become a lucrative business. Companies are selling a myriad of different CBD oils and other products in an attempt to cash in on the new health trend. This means there are a lot of excellent products coming to market, but it also means there’s a lot of trash as well. It’s important as a CBD user that you understand what makes a CBD oil good, and what makes it bad so you can avoid wasting your money, or worse — using CBD oils that contain harmful or damaging ingredients.
Let’s cover the most important points to remember when looking for CBD oil online retailers.
1. Check the Hemp Source
The source of the hemp used to make the oil is vitally important when it comes to determining which CBD oils are the best. The main reason comes down to the botany of the hemp plant itself.
Hemp is a bio-accumulator — which means it has the tendency to absorb compounds from the soil and accumulate them in its leaves, stems, and roots. The deep taproots of the hemp plant stretch far beneath the soil, pulling out and storing all the heavy metals and other elements it can find in the soil.
This aspect is in part why hemp is so nutritious, but it also means that plants grown in contaminated soils often contain contaminants that can be harmful to your health. Some of the worst offenders are heavy metals — which can build up in the body over time and lead to severe long-term health effects.
You want to avoid consuming heavy metals at all costs.
Poorly grown hemp could contain heavy metals, as well as other contaminants like mycotoxins, or pesticide residues that will end up in the CBD oil after all the processing is complete.
For this reason, it’s important to purchase CBD oil from companies that account for this effect. Only buy from company’s that make an effort to source hemp from organic farms, and take measures to assess every batch of hemp that enters the facility to determine heavy metal, microbial contaminant, and pesticide contamination.
The best hemp sources tend to come from states like Oregon, Colorado, or Alabama, as well as neighboring countries like Canada or Scandinavian countries. These places are all known for having high standards for hemp cultivation, and clean soils.
2. Look for CO2 Extracted Products
Once the company has the hemp, they need to extract the CBD from it. You can do this in many different ways using solvents like ethanol, methanol, hexane, ether, or butane. All of these solvents work to strip the active compounds from the hemp plant and can then be evaporated to leave behind a pure CBD-rich resin.
however, there’s a problem with these solvents.
Even in professional lab settings, it can be very difficult to remove all traces of these solvents from the final product. Most of these solvents are toxic to the human body, even in trace amounts.
Therefore, the best companies are using another method to strop the active ingredients from the starting hemp material. This method uses CO2 placed under high pressure. the high pressure and temperature control convert the CO2 into a phase that’s neither liquid nor gas. This special state is referred to as being supercritical.
Supercritical CO2 acts just like any other solvent, but with one key benefit — as soon as the pressure is relieved, the gas evaporates completely, leaving behind no harmful chemical residues.
when shopping for CBD oil, it’s ideal to look for a company that uses supercritical CO2 to extract the CBD rather than the toxic solvents mentioned above. Supercritical CO2 is very expensive and highly technical — but usually produces a far superior product in the end.
If a company is using harsh solvents like butane or propane (or they don’t tell you anything about their extraction methods), it’s a sign that you should look for another brand.
3. Ask for Third-Party Lab Reports
Every company has the option to send their products to an independent lab or third-party testing.
These laboratory tests check for the entire cannabinoid profile of the extract and are able to detect over 200 common contaminants.
Before a CBD product becomes available for sale, it should pass the laboratory test for potency and purity. If any inconsistencies are shown between different batches of the same product, the company should rework it and send it for analysis once again.
High-quality CBD companies will continually send each batch of product to a lab with no affiliation to the company (called a third-party or independent lab) for testing. These results are then published publicly on the website for customers to view.
The best companies will take this even one step further — adding a database and batch numbers on every bottle of CBD oil so you can view the results for your specific bottle of oil. Third-party testing is now an industry standard.
Always buy your CBD oil from companies that show third-party lab reports on their website. Only then will you know what’s inside the bottle before you even order a product. If the company is producing CBD oil that’s as high quality, as they say, there should be nothing to hide in these lab tests and they should be listed publicly on the company website. If you can’t find them on the site, you can ask customer service for these as well.
If these tests don’t exist, or you can’t track them down from the website or customer service — it’s best to avoid this company and move on to another that takes this important step seriously.
What the Research Says About Using CBD Oil for Pain:
Understanding how CBD works is no simple task. This compound is incredibly complex — working through a number of unrelated receptors around the body, interacting with enzymes, cell membranes, and various other cell structures. This makes studying CBD very difficult.
Nevertheless, there have been thousands of research papers published on medical marijuana — seeking to understand the interaction between cannabinoids like CBD and the human body. A lot of this research specifically focused on the effects of CBD on various forms and causes of pain. Let’s explore some of the results this research has yielded in the context of pain management.
1. CBD Oil for Chronic Back & Nerve Pain
The painkilling properties of cannabidiol have been most thoroughly studied in animal models, as well as a handful of human clinical trials.
One of the best studies we have available on the topic is a meta-analysis published in 2017. This analysis looked at 24 different clinical trials involving 1,334 patients over several years and demographics. These studies all used various forms of cannabis for treating chronic pain. The analysis reports that many of these studies showed a reduction in chronic pain scores by 50% or more (3) — suggesting the cannabis plant to be a potential treatment for chronic pain.
Another clinical trial looked at the effects of a combination of CBD to THC in the treatment of intractable cancer pain. This study found that twice as many people in the treatment group given CBD and THC had a 30% or more reduction in pain symptoms at the conclusion of the trial (6).
Even though more clinical trials on humans are needed to gauge how CBD affects specific forms of pain or other conditions, scientists believe the efficacy of CBD in treating chronic pain is related to its anti-inflammatory effects (3).
2. CBD Oil for Arthritis
CBD has had a lot of research as a potential alternative to prescription and non-prescription pain medications commonly used for alleviating arthritis pain.
Researchers have found a clear link between the endocannabinoid system and the pathophysiology of osteoarthritis, which is a degenerative joint disease associated with chronic pain and inflammation (4).
One of the key areas CBD is thought to support osteoarthritis specifically is through the effects on an enzyme known as 5-lipoxygenase — AKA 5-LOX. CBD has been shown to inhibit this enzyme (7), which converts fatty acids into pro-inflammatory compounds. These inflammatory messengers have been shown to be a key component in the underlying inflammation involved with osteoarthritis (8).
By reducing the underlying causes of arthritis pain, CBD is thought to reduce the overall burden of pain from the condition over the long term.
3. CBD and Multiple Sclerosis (MS) Pain
Due to its antioxidant and anti-inflammatory properties, CBD is a potent neuroprotective — which is how experts believe CBD is able to relieve debilitating MS pain, —which affects roughly 50–70% of patients diagnosed with the condition.
A study conducted on animals at Cajan Institute tested the anti-inflammatory effects of CBD on mice the researchers wanted to find out if CBD can provide a reversed inflammatory response on those cells. After ten days, the researchers found a reduction in inflammatory markers with a rodent encephalitis model designed to imitate the impact MS has on the body (5).
More research is needed to see exactly how these effects are translated to humans. Currently, there are 23 clinical trials currently underway, or planned within the next 12 months seeking to explore the effects of CBD on MS.
4. CBD Oil in Sports: Injuries & Muscle Endurance
Cannabidiol can be applied in two different ways when it comes to pain and physical activities. For example, when you administer CBD orally in the form of oil as a post-workout, it helps alleviate the muscle inflammation that troubles athletes once they go beyond the edge again.
If, however, you’re suffering from an injury, it’s best to apply CBD topically. Its anti-inflammatory and neuroprotective properties allow the cannabinoid to relieve pain and improve regeneration capacities.
Does CBD Have Any Side Effects?
The main reason why parents are so enthusiastic about CBD is that this cannabinoid is completely non-intoxicating, doesn’t cause addiction, and has only a few mild side effects when taken at excessive doses.
Research shows that even doses up to one and a half grams have no severe side effects on human health (9).
Despite being a notoriously safe supplement, there are some side effects of using CBD in high doses. Let’s cover the most common side effects people report from using CBD:
- Brain fog
- Reduced appetite
- Mood changes
- Diarrhea or constipation
- Dizziness or lightheadedness
- Drowsiness or fatigue
- Dry mouth
- Nausea and vomiting
The most common side effect by far, like other forms of cannabis, is dry mouth. This is best managed by taking your CBD oil along with some juice like pineapple or orange juice.
Another common side effect is lowered blood pressure, which may trigger another unwanted reaction — lightheadedness. This side effect is important to consider if you suffer from low blood pressure already or are taking blood pressure-lowering medications.
Always consult your doctor before using CBD or other cannabis extracts if you’re taking prescription medications or have underlying medical conditions.
In Summary: Buying CBD Oil For Pain
As CBD becomes more popular around the world, scientists are publishing new research on cannabinoids on a near-weekly basis. As time goes on, experts are mapping out the complicated mechanisms CBD and other hemp derivatives are using to support both acute and chronic pain of all different origins.
Here are the main takeaways from the current research:
- CBD inhibits inflammation at several different levels
- CBD offers antioxidant support
- CBD may relieve muscle tension and inflammation
- CBD interacts with the vanilloid receptors in the brain responsible for regulating inflammatory pain transmission
When it comes to pain, CBD appears to target the cause of the problem instead of just masking its symptoms.
Getting relief on so many levels and without any harmful side effects or risk of addiction is the reason why CBD oil has become so popular over the past half a decade.
I hope this guide has managed to clear up any confusion regarding CBD oil and pain, and given you the insight necessary to find the right CBD oil for the job.
Have you tried CBD oil for chronic pain? Did you feel any difference? Let me know in the comments below!
- Brand, E. J., & Zhao, Z. (2017). Cannabis in Chinese Medicine: Are Some Traditional Indications Referenced in Ancient Literature Related to Cannabinoids?. Frontiers in pharmacology, 8, 108.
- Alger B. E. (2013). Getting high on the endocannabinoid system. Cerebrum: the Dana forum on brain science, 2013, 14.
- Aviram, J., Samuelly-Leichtag, G. (2017) Efficacy of Cannabis-Based Medicines for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pain Physician, 20(6), E755-E796.
- Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). Cannabinoid Delivery Systems for Pain and Inflammation Treatment. Molecules (Basel, Switzerland), 23(10), 2478.
- Elliott, D. M., Singh, N., Nagarkatti, M., & Nagarkatti, P. S. (2018). Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. Frontiers in immunology, 9, 1782.
- Johnson, J. R., Burnell-Nugent, M., Lossignol, D., Ganae-Motan, E. D., Potts, R., & Fallon, M. T. (2010). Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC: CBD extract and THC extract in patients with intractable cancer-related pain. Journal of pain and symptom management, 39(2), 167-179.
- Takeda, S., Usami, N., Yamamoto, I., & Watanabe, K. (2009). Cannabidiol-2′, 6′-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor. Drug Metabolism and Disposition.
- Lascelles, B. D. X., King, S., Roe, S., Marcellin‐Little, D. J., & Jones, S. (2009). Expression and activity of COX‐1 and 2 and 5‐LOX in joint tissues from dogs with naturally occurring coxofemoral joint osteoarthritis. Journal of orthopaedic research, 27(9), 1204-1208.Chicago
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
How To Use CBD To Help Manage Pain
Dr. Bindiya Gandhi is an integrative medicine physician with expertise in functional and holistic medicine based in Atlanta, Georgia.
Commissions we earn from partner links on this page do not affect our opinions or evaluations. Our editorial content is based on thorough research and guidance from the Forbes Health Advisory Board.
Table of Contents
- CBD for Pain Relief
- CBD for Chronic Pain
- CBD for Arthritis and Joint Pain
- CBD for Neuropathic Pain
Without the intoxicating properties of its cousin delta-9-tetrahydrocannabinol (THC), cannabidiol (CBD) can provide the human body with a handful of health benefits. Cannabinoids like CBD interact with receptors in the endocannabinoid system, which plays a role in signaling bodily functions, from emotional responses to motor control to energy balance  Mouslech Z, Valla V. Endocannabinoid system: An overview of its potential in current medical practice. Neuro Endocrinol Lett. 2009;30(2):153-179. .
Over the last two decades, scientists have tested CBD’s efficacy as an analgesic, or painkiller, specifically—and with promising results. While research is ongoing, here’s what we know so far about how we can use CBD oil for pain relief.
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CBD for Pain Relief
For now, no CBD-based medications are approved as painkillers in the U.S. Epidiolex, which is used for rare forms of epilepsy, is the only CBD treatment approved by the Food and Drug Administration (FDA).
Meanwhile, several countries have approved CBD to treat certain conditions. For instance, the U.K. approved it for multiple sclerosis, and Canada approved it for cancer pain. Ongoing research suggests CBD oil for pain can aid medical conditions, including arthritis and fibromyalgia, at varying doses. Some pain may not be treatable by CBD alone, but it can help when paired with THC or Western medication applications.
Interestingly, 60% of U.S. adults who use CBD products do so for its potential pain-relieving effects, according to a recent Forbes Health survey of 2,000 U.S. adults conducted by OnePoll.
What’s more, 60% of U.S. adults have tried CBD and believe it has medicinal benefits.
CBD for Chronic Pain
Chronic pain is defined as any pain lasting longer than several months. Studies have found CBD, often alongside THC, to be an effective pain reliever for various chronic conditions.
In clinical trials, Sativex, a spray with equal parts CBD and THC, proved significantly successful as an analgesic for cancer-related pain  Russo EB. Cannabinoids in the management of difficult to treat pain. Ther Clin Risk Manag. 2008;4(1):245-259. . The spray, also used for multiple sclerosis-related pain, is approved in Canada to treat cancer pain and is currently undergoing trials for approval and use in the U.S.
A 2019 study found Sativex to be an “effective and well-tolerated add-on treatment” for patients with severe chronic pain stemming from various ailments. The study identified three types of pain: nociceptive (affecting body tissue), neuropathic (affecting nerves) and mixed pain. Sativex helped treat all three kinds but proved especially effective against neuropathic pain.
An earlier study also found CBD to be effective in chronic pain relief for conditions like multiple sclerosis and spinal cord injury, although across a much smaller sample size  Wade DT, Robson P, House H, Makela P, Aram J. A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms. Clin Rehabil. 2003;17(1):21-29. .
CBD for Arthritis and Joint Pain
Arthritis is a broad term that encompasses hundreds of joint-related conditions and pains. Common symptoms include swelling, pain and stiffness in the joints and may progress over time.
Already a proven analgesic for other conditions, CBD shows promise as an anti-inflammatory substance in both animal and preclinical trials, which bodes well for arthritis treatment  Nichols JM, Kaplan BLF. Immune Responses Regulated by Cannabidiol. Cannabis Cannabinoid Res. 2020;5(1):12-31.  Mlost J, Bryk M, Starowicz K. Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action. Int J Mol Sci. 2020;21(22):8870.  Kosgodage US, Mould R, Henley AB, et al. Cannabidiol (CBD) Is a Novel Inhibitor for Exosome and Microvesicle (EMV) Release in Cancer. Front Pharmacol. 2018;9:889.  Lowin T, Tingting R, Zurmahr J, Classen T, Schneider M, Pongratz G. Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts. Cell Death Dis. 2020;11(8):714. . However, clinical research dedicated to CBD administration for arthritis is less robust and ongoing.
The first controlled trial conducted in 2006 focused on patients with rheumatoid arthritis, an autoimmune disease that causes inflammation in the joints and other affected areas  Blake DR, Robson P, Ho M, Jubb RW, McCabe CS. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine (Sativex) in the treatment of pain caused by rheumatoid arthritis. Rheumatology (Oxford). 2006;45(1):50-52. . Researchers found that, compared to a placebo, Sativex significantly improved participants’ pain during movement, pain at rest and quality of sleep. Any adverse reactions to the treatment were mild or moderate, and there were no complications with withdrawal.
In 2018 researchers tested the efficacy of topical CBD gel on participants with osteoarthritis-related knee pain over the course of 12 weeks  Hunter D, Oldfield G, Tich N, Messenheimer J, Sebree T. Synthetic transdermal cannabidiol for the treatment of knee pain due to osteoarthritis. Osteoarthritis and Cartilage. 2018;26:S26. . Participants used either 250 milligrams or 500 milligrams, split into two applications, daily. Overall, participants’ weekly pain levels didn’t improve much with CBD compared to placebo. However, when researchers evaluated the average weekly worst pain scores and Western Ontario and McMaster Universities Arthritis Index (WOMAC) physical function scores, participants who applied 250 milligrams of CBD daily experienced significant improvement over placebo participants.
Meanwhile, a small 2019 trial suggests a mix of CBD and THC may prove beneficial for people with fibromyalgia, a type of arthritis that results in whole-body pain and fatigue  van de Donk T, Niesters M, Kowal MA, Olofsen E, Dahan A, van Velzen M. An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia. Pain. 2019;160(4):860-869. . The study found that, via a single inhalation, a CBD-THC solution performed better than a placebo and either substance on its own.
CBD for Neuropathic Pain
Various conditions and injuries that damage nerves or the nervous system can result in neuropathic pain. This kind of pain manifests as tingling, numbness, muscle weakness and a sharp, shooting, burning or stabbing pain.
Multiple sclerosis (MS) is a common cause of neuropathic pain. The disease wears down myelin, a mixture of proteins and phospholipids that coats nerve cells. Sativex is already approved as an MS treatment around the world due to its success in clinical trials. As a spray, Sativex is absorbed in the mouth. Studies support a median dose of eight sprays a day for patients with MS, which provides about 20 milligrams of CBD and 21.6 milligrams of THC  Sativex Oromucosal Spray – Summary of Product Characteristics (SmPC). Datapharm. Accessed 7/9/2021. . However, doses vary between patients, and each person needs to find their optimal dose.
A 2020 study also tested topically administered CBD oil as a treatment for patients with peripheral neuropathy, or damage to the peripheral nervous system, which sends information throughout your body from the central nervous system  Xu DH, Cullen BD, Tang M, Fang Y. The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities. Curr Pharm Biotechnol. 2020;21(5):390-402. . When compared to placebo, the topical CBD significantly reduced patients’ intense pain and sharp pain, as well as cold and itchy sensations.
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